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Viewing: BME 325 : Biochemistry for Biomedical Engineers

Last approved: Fri, 08 Dec 2017 09:02:04 GMT

Last edit: Thu, 07 Dec 2017 20:55:18 GMT

Change Type
Major
BME (Biomedical Engineering)
325
032536
Dual-Level Course
Cross-listed Course
No
Biochemistry for Biomedical Engineers
BiochemistryforBME
College of Engineering
Biomedical Engineering (14BME)
Term Offering
Fall Only
Offered Every Year
Fall 2018
Previously taught as Special Topics?
No
 
Course Delivery
Face-to-Face (On Campus)

Grading Method
Letter Grade Only
3
16
Contact Hours
(Per Week)
Component TypeContact Hours
Lecture3
Course Attribute(s)


If your course includes any of the following competencies, check all that apply.
University Competencies

Course Is Repeatable for Credit
No
 
 
Michael Gamcsik
Associate Professor

Open when course_delivery = campus OR course_delivery = blended OR course_delivery = flip
Enrollment ComponentPer SemesterPer SectionMultiple Sections?Comments
Lecture4040NoThis course is a gateway elective and it is being offered every semester.
Open when course_delivery = distance OR course_delivery = online OR course_delivery = remote
Prerequisite: CH 221, (BME 209 or BME 203)

Is the course required or an elective for a Curriculum?
Yes
SIS Program CodeProgram TitleRequired or Elective?
14BMEBSBiomedical EngineeringElective
An overview of how alterations in bioenergetics, enzyme catalysis, protein and membrane structure, carbohydrate, lipid and nucleic acid metabolism affect human health and how biomedical engineering tools are used to detect and monitor the problems by understanding these biochemical processes. Topics include: Biological Thermodynamics, Energy of macromolecular structure and binding, Structure/function of proteins, enzymes and nucleic acids, Kinetics, enzyme catalysis and biochemical network analysis, Generation of chemical and electrical potential in membranes, Carbohydrate/lipid/protein metabolism and energy production, DNA synthesis, transcription, Technologies used to monitor/detect biochemical processes including clinical imaging modalities.

Biomedical Engineering program is going through a major curriculum change and creating a unified undergraduate curriculum between NCSU and UNC-CH. BME 325 is one of the eight gateway electives which prepare the students for the specialization electives in five areas of faculty interest. BME 325 shows the biochemical underpinnings of pharmacoengineering, regenerative medicine, rehabilitation engineering, micro devices and imaging.


No

Is this a GEP Course?
No
GEP Categories

Humanities Open when gep_category = HUM
Each course in the Humanities category of the General Education Program will provide instruction and guidance that help students to:
 
 

 
 

 
 

 
 

 
 

 
 

Mathematical Sciences Open when gep_category = MATH
Each course in the Mathematial Sciences category of the General Education Program will provide instruction and guidance that help students to:
 
 

 
 

 
 

 
 

Natural Sciences Open when gep_category = NATSCI
Each course in the Natural Sciences category of the General Education Program will provide instruction and guidance that help students to:
 
 

 
 

 
 

 
 

Social Sciences Open when gep_category = SOCSCI
Each course in the Social Sciences category of the General Education Program will provide instruction and guidance that help students to:
 
 

 
 

 
 

 
 

 
 

 
 

Interdisciplinary Perspectives Open when gep_category = INTERDISC
Each course in the Interdisciplinary Perspectives category of the General Education Program will provide instruction and guidance that help students to:
 
 

 
 

 
 

 
 

 
 

 
 

 
 

 
 

Visual & Performing Arts Open when gep_category = VPA
Each course in the Visual and Performing Arts category of the General Education Program will provide instruction and guidance that help students to:
 
 

 
 

 
 

 
 

 
 

 
 

Health and Exercise Studies Open when gep_category = HES
Each course in the Health and Exercise Studies category of the General Education Program will provide instruction and guidance that help students to:
 
 

 
 

 
 

 
 

 
&
 

 
 

 
 

 
 

Global Knowledge Open when gep_category = GLOBAL
Each course in the Global Knowledge category of the General Education Program will provide instruction and guidance that help students to achieve objective #1 plus at least one of objectives 2, 3, and 4:
 
 

 
 

 
Please complete at least 1 of the following student objectives.
 

 
 

 
 

 
 

 
 

 
 

US Diversity Open when gep_category = USDIV
Each course in the US Diversity category of the General Education Program will provide instruction and guidance that help students to achieve at least 2 of the following objectives:
Please complete at least 2 of the following student objectives.
 
 

 
 

 
 

 
 

 
 

 
 

 
 

 
 

Requisites and Scheduling
 
a. If seats are restricted, describe the restrictions being applied.
 

 
b. Is this restriction listed in the course catalog description for the course?
 

 
List all course pre-requisites, co-requisites, and restrictive statements (ex: Jr standing; Chemistry majors only). If none, state none.
 

 
List any discipline specific background or skills that a student is expected to have prior to taking this course. If none, state none. (ex: ability to analyze historical text; prepare a lesson plan)
 

Additional Information
Complete the following 3 questions or attach a syllabus that includes this information. If a 400-level or dual level course, a syllabus is required.
 
Title and author of any required text or publications.
 

 
Major topics to be covered and required readings including laboratory and studio topics.
 

 
List any required field trips, out of class activities, and/or guest speakers.
 

BME department had 8 recent hires to cover the teaching load required by the new curriculum."

The goal of this course is to show how biomedical engineering tools are used to detect, monitor and treat human health problems by understanding the biochemical processes behind them.


Student Learning Outcomes

By the end of this course, students will be able to


1. Explain how energy is derived from the diet and used to perform biochemical and mechanical work


2. Determine whether chemical reactions will proceed spontaneously under physiologic conditions


3. Describe how enzymes facilitate and control biochemical reactions


4. Derive the Michaelis-Menten Equation


5. Generate the differential equations describing the time dependence of the concentration of metabolites in a biochemical network.


6. Use SimBiology in Matlab to model, simulate and analyze dynamic systems.


7. Explain how energy minimization drives macromolecular structures and binding processes


8. Explain how membranes generate and maintain chemical and electrical potential.


9. Describe how the genetic code is transcribed and translated.


10. Explain the principles behind the technologies used to analyze biochemical components.


11. Describe the chemical principles underlying medical imaging technologies


12. Predict how drug chemical/structural properties influence the delivery and uptake in tissue


13. Provide examples of the contributions of biochemistry to the fields of pharmacoengineering and regenerative medicine.


Evaluation MethodWeighting/Points for EachDetails
Homework15Five homework assignments are posted on the course website and to be completed by all students over the course of the semester. Each assignment can be submitted electronically through the website, email or paper hardcopy at the start of class for each for each due date. Each assignment will consist of 5 - 10 question in short answer or essay format.
Multiple exams40Two hourly exams will be administered during the semester with each worth 20% of the total grade. Typical exams consist of 5 - 10 short answer or essay-type questions on paper to be completed during the class period.
Final Exam20The final exam will cover the material from the last semester exam to the end of the course. The final will consist of 5 - 10 short answer or essay-type questions on paper to be completed during the class period.
Quiz15Three quizzes will be given over the course of the semester. These will usually consist of 3-5 multiple choice, true/false or short answer questions on paper that will take approximately 5 minutes to complete at the beginning of class and will cover course content from previous classes.
Forum_post5Warm up questions are posted online on the course website before every class lecture. They will be available to students at the completion of each class in preparation for the next class. Each Warm Up Question consists of 3 - 7 multiple choice questions that are posted via the class website. The quiz questions will cover material that will be presented in the next class so students may use any resource (textbook, Google, etc) to answer these questions.
Participation53%       Attendance:
• 3% 0 – 1 unexcused absences
• 2% 2 – 3 unexcused absences
• 0% >3 unexcused absences
 
2%       In-class/online contributions:  
• 2%       Regularly (weekly) volunteers answers to general class questions; or Regularly (weekly) asks questions in class lectures or Regularly (weekly) contributions online lecture evaluations/questions
• 1%       Offers occasional (monthly) answers/questions online or in-class
• 0%       No interaction in class or online
Topical Outline/Course Schedule is included in the syllabus
dwparish (Wed, 20 Sep 2017 19:05:15 GMT): Rollback: Rolled back by request
dwparish (Mon, 25 Sep 2017 14:21:36 GMT): Rollback: needs corrections as per CCC
aeherget (Sat, 25 Nov 2017 16:29:08 GMT): AECHH: Uploading updated syllabus at initiator's request via email 11/22/2017.
Key: 16684