By the end of this course, students will be able to
1. Explain how energy is derived from the diet and used to perform biochemical and mechanical work
2. Determine whether chemical reactions will proceed spontaneously under physiologic conditions
3. Describe how enzymes facilitate and control biochemical reactions
4. Derive the Michaelis-Menten Equation
5. Generate the differential equations describing the time dependence of the concentration of metabolites in a biochemical network.
6. Use SimBiology in Matlab to model, simulate and analyze dynamic systems.
7. Explain how energy minimization drives macromolecular structures and binding processes
8. Explain how membranes generate and maintain chemical and electrical potential.
9. Describe how the genetic code is transcribed and translated.
10. Explain the principles behind the technologies used to analyze biochemical components.
11. Describe the chemical principles underlying medical imaging technologies
12. Predict how drug chemical/structural properties influence the delivery and uptake in tissue
13. Provide examples of the contributions of biochemistry to the fields of pharmacoengineering and regenerative medicine.