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Viewing: CBS 750 : Techniques in Pharmacological Research

Last approved: Fri, 19 Jan 2018 14:42:26 GMT

Last edit: Fri, 19 Jan 2018 14:42:26 GMT

Formerly Known As: CBS 860


Change Type
Major
CBS (Comparative Biological Science)
750
002700
Dual-Level Course
Cross-listed Course
No
Techniques in Pharmacological Research
Tech in Pharm Research
College of Veterinary Medicine
CVM Deans Office (19DVM)
Term Offering
Spring Only
Offered Every Year
Spring 2018
Previously taught as Special Topics?
No
 
Course Delivery
Face-to-Face (On Campus)

Grading Method
Graded/Audit
2
16
Contact Hours
(Per Week)
Component TypeContact Hours
Lecture1.0
Laboratory4.0
Course Attribute(s)


If your course includes any of the following competencies, check all that apply.
University Competencies

Course Is Repeatable for Credit
Yes
8
 
 
1
Ronald Baynes
Professor of Pharmacology
Full

Open when course_delivery = campus OR course_delivery = blended OR course_delivery = flip
Enrollment ComponentPer SemesterPer SectionMultiple Sections?Comments
Lecture1010Non/a
Open when course_delivery = distance OR course_delivery = online OR course_delivery = remote
Prerequisite: BCH 452B or CH 315 or Equivalent and Graduate standing
Is the course required or an elective for a Curriculum?
Yes
SIS Program CodeProgram TitleRequired or Elective?
19CBSCBPDRComparative Biomedical Sciences Pharmacology ConcentrationRequired
Theory and applications of modern scientific instrumentation to analysis of tissues, body fluids and drugs in pharmacological research. Discussion of appropriate aspects of the pharmacological use of spectroscopy, microscopy, chromatography, electrophoresis, radioisotope usage and centrifugation.

The previous faculty member teaching this course left the University. Dr. Baynes is taking over the course and will be henceforth offering the course in spring, since he has teaching conflicts that prevent offering the course in fall.


No

Is this a GEP Course?
GEP Categories

Humanities Open when gep_category = HUM
Each course in the Humanities category of the General Education Program will provide instruction and guidance that help students to:
 
 

 
 

 
 

 
 

 
 

 
 

Mathematical Sciences Open when gep_category = MATH
Each course in the Mathematial Sciences category of the General Education Program will provide instruction and guidance that help students to:
 
 

 
 

 
 

 
 

Natural Sciences Open when gep_category = NATSCI
Each course in the Natural Sciences category of the General Education Program will provide instruction and guidance that help students to:
 
 

 
 

 
 

 
 

Social Sciences Open when gep_category = SOCSCI
Each course in the Social Sciences category of the General Education Program will provide instruction and guidance that help students to:
 
 

 
 

 
 

 
 

 
 

 
 

Interdisciplinary Perspectives Open when gep_category = INTERDISC
Each course in the Interdisciplinary Perspectives category of the General Education Program will provide instruction and guidance that help students to:
 
 

 
 

 
 

 
 

 
 

 
 

 
 

 
 

Visual & Performing Arts Open when gep_category = VPA
Each course in the Visual and Performing Arts category of the General Education Program will provide instruction and guidance that help students to:
 
 

 
 

 
 

 
 

 
 

 
 

Health and Exercise Studies Open when gep_category = HES
Each course in the Health and Exercise Studies category of the General Education Program will provide instruction and guidance that help students to:
 
 

 
 

 
 

 
 

 
&
 

 
 

 
 

 
 

Global Knowledge Open when gep_category = GLOBAL
Each course in the Global Knowledge category of the General Education Program will provide instruction and guidance that help students to achieve objective #1 plus at least one of objectives 2, 3, and 4:
 
 

 
 

 
Please complete at least 1 of the following student objectives.
 

 
 

 
 

 
 

 
 

 
 

US Diversity Open when gep_category = USDIV
Each course in the US Diversity category of the General Education Program will provide instruction and guidance that help students to achieve at least 2 of the following objectives:
Please complete at least 2 of the following student objectives.
 
 

 
 

 
 

 
 

 
 

 
 

 
 

 
 

Requisites and Scheduling
 
a. If seats are restricted, describe the restrictions being applied.
 

 
b. Is this restriction listed in the course catalog description for the course?
 

 
List all course pre-requisites, co-requisites, and restrictive statements (ex: Jr standing; Chemistry majors only). If none, state none.
 

 
List any discipline specific background or skills that a student is expected to have prior to taking this course. If none, state none. (ex: ability to analyze historical text; prepare a lesson plan)
 

Additional Information
Complete the following 3 questions or attach a syllabus that includes this information. If a 400-level or dual level course, a syllabus is required.
 
Title and author of any required text or publications.
 

 
Major topics to be covered and required readings including laboratory and studio topics.
 

 
List any required field trips, out of class activities, and/or guest speakers.
 

This course will be taught by rotating in CVM pharmacology faculty laboratories to observe and be trained to use and apply various technologies common to pharmacological research.

The students will be expected to be proficient in the theory and applications of modern scientific instrumentation to analysis of tissues, body fluids and drugs in pharmacological research including  spectroscopy, microscopy, chromatography, electrophoresis, radioisotope usage and centrifugation.


Student Learning Outcomes

By the end of this course, the students will be able to:



  1. Accurately prepare drug solutions using standard analytical equipment and prepare an accurate standard curve.

  2. Differentiate between accuracy and precision of analytical chemistry methods.

  3. Explain the basic chromatography concepts as it pertains to analytical chemistry.

  4. Differentiate between liquid chromatography and gas chromatography methods.

  5. Explain the basic principles of mass spectrometry.

  6. Measure drug-protein binding and cellular proteins

  7. Explain basic pharmaceutical techniques in preparation of drug formulations

  8. Record, analyze, and summarize laboratory findings in laboratory notebook.


Evaluation MethodWeighting/Points for EachDetails
Lab Report60Competency in performing basic analytical techniques in the laboratory
Project30Adequate completion of assigned projects
Other10Quality of recording and reporting in laboratory note books of projects
TopicTime Devoted to Each TopicActivity
Caffeine Project4 hoursProper use of analytical balance and pipette
Calculate dilutions
Set up standard curve
Use of HPLC
Chromatography Project4 hoursSample preparation
Set up standard curve
Quantify drug concentration from matrix
We would like to change the grading method to be for letter grade as indicating on the attached syllabus.

mlnosbis 8/2/2017:
1) The course cannot be letter graded because it is an 800-level course (see https://projects.ncsu.edu/grad/handbook/sections/3.19-graduate-courses.html). If you want this course to be letter graded, you will need to edit the course number to a 700-level course.
2) Regarding the prerequisites: will all doctoral students be required to take BCH 452 or CH 315 at NC State, or do you think you want to add "or equivalent" to account for students who may have taken an equivalent at a different school?
3) Syllabus notes:
-See the attached Graduate Course Syllabus Checklist, make sure the syllabus has all required parts (items 1-14). This syllabus is missing many of the required components.
-If you're not going to list readings on the syllabus, then remove that column from the weekly topic chart.
-What are the various projects that comprise 30% of the grade? Consider listing them separately in the evaluation methods.

pjharrie 8/21/2017 - as noted by Melissa, there are numerous places where there isn't sufficient detail to evaluation this course.

ABGS Reviewer Comments:
-No concerns.
rebaynes (Tue, 22 Aug 2017 17:10:17 GMT): Please change the course number to CBS 750 I do not see he section on reading list; please remove if still there. I have expanded on the various project for 30% with listing of what is being evaluated in these projects. Please attachment for revised document.
mlnosbis (Thu, 24 Aug 2017 12:19:55 GMT): Rollback: Please edit the syllabus as suggested in the Additional Comments section and so the syllabus adheres to the Graduate Syllabus checklist. Make more presentable as a syllabus instead of just listing sentences; consider using the syllabus tool.
Key: 828