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Comparative Biological Science (CBS)

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  • CBS - Comparative Biological Science Courses

    CBS 493 Undergraduate Research in Biomedical Sciences 1-3.
    Requisite: Sophomore Standing or Above.

    A learning experience in College of Veterinary Medicine within an academic framework that utilizes campus facilities and resources for supervised undergraduate research. Arrangements must be initiated by the student and be approved by a faculty adviser, the college Undergraduate Research Coordinator, and the Associate Dean of Research Training and Graduate Programs. Students who enroll in this course are required in this course to complete and submit an Agreement for Non-Standard Courses form through Registration and Records.

    CBS 510 Animal Production Topics 1-3.

    Students will be provided with experience in management of production animals with an emphasis on the veterinary aspects of population health. Experience will come in the form of hands-on experiences and working through relevant literature to specific and relevant population health issues.

    CBS 550 Population Medicine Forum 1.

    Population medicine forum is a seminar-based class during which current topics in population health are presented and discussed. Topics covered include: Outbreak investigation, observational epidemiologic research, risk analysis, spatial analysis, the application of unique diagnostic technologies and epidemiologic modeling.

    CBS 554 Trade and Agricultural Health 2.
    Prerequisite: Graduate standing, Upper Class Undergraduate standing.

    This course is designed for agriculture and food safety specialists, veterinarians, and epidemiologists interested in learning about international trade and agricultural health. WTO/SPS affect all aspects of agricultural health including production,food security, public health, tourism and the environment. This introductory course will review SPS articles, GATT provisions, the associations between WTO and public health, the work of the OIE, CAC, and IPPC; the impact of TRIPS and anti-dumping measures.

    CBS 565 Fundamentals of Biomedical Sciences 3.

    Introductory course for students interested in gaining a broad understanding of: comparative genomics, comparative immunology, comparative physiology, pharmacokinetics, emerging zoonotic diseases, epidemiology and translational research models and methods. This course also provides an overview of current technologies relevant to comparative biomedical research and a foundation for implementing the scientific method (e.g. experimental design, data analyses, statistics). Priority will be given tofirst-year students in CBS graduate program; Enrollment of all students requires consent of instructor.

    CBS 570 Methods in Biomedical Sciences 1.

    Introductory course for students interested in gaining a broad understanding of various laboratory methods used in molecular, cellular and "omics" based biomedical research.

    CBS 579 Advanced Specialty Training 1-3.

    This course is designed to give students clinical experience and training to understand basic health management strategies, handle clinical evaluations, use diagnostic tools to facilitate accurate diagnosis, and develop prevention and/or treatment plans for health management. This course is restricted to Students in the SVM program.

    CBS 580 Clinical Veterinary Epidemiology 3.
    Prerequisite: ST 511.

    To expose students to the concepts and principles of epidemiology from the perspective of assessing health and disease in animal and human populations, and the measures to control disease status. Specifically to study the principles and concepts ofveterinary epidemiology, to learn basic epidemiology methodology, critically review major veterinary care studies, and enhance oral and written communication skills.

    CBS 595 Special Topics 1-6.

    CBS 602 Seminar In Biology Of Reproduction 2.
    Prerequisite: ANS(PHY) 702.

    Current topics in animal reproduction presented by reproductive physiologists from various Research Triangle institutions. Student presentations of research projects or library projects in area of animal reproduction.

    CBS 610 Special Topics In Veterinary Medical Sciences 1-6.
    Prerequisite: Senior standing or Graduate standing.

    Designed to present new or special subject matter within the scope of pathology, veterinary microbiology, morphology or pharmacology. The studies may include independent investigations, seminars and/or formal lectures.

    CBS 615 Advanced Animal Production Topics 1-3.
    Prerequisite: SVM 510.

    Students will be provided with practice and experience in advanced topics related to management of production animals with an emphasis on the veterinary aspects of population health. Actual in-the-field, hands-on practice and investigation of relevant literature will provide the basis for study of advanced animal production topics.Course is restricted to students in the SVM program.

    CBS 624 Special Problems In Gastrointestinal Physiology 1.

    1 credit for a 1-hour in depth discussion session of current journal articles presented by students on the subject of gastrointestinal physiology. Journals recommended include the American Journal of Physiology, Gut and Gastroenterology. Each session will focus on one student's selected paper. MS students are expected to present 1 paper, and PhD students are expected to present up to 2 papers each semester. Students should be enrolled in a graduate course of study in a field related to or focused on physiology. Undergraduate students require special permission.

    CBS 635 MR Advanced Reading 1-3.

    CBS 649 Issues in Preventive Medicine and Public Health 1.
    Prerequisite: A prior degree in veterinary medicine or public health.

    Issues in Preventive Medicine and Public Health is a literature review course designed to assist students with their preparation for careers in public health, ecosystem health, biosecurity and public policy, disaster management, and application for Board Certification in the American College of Preventive Veterinary Medicine. Permission by course instructor required for enrollment.

    CBS 650 Population Medicine Forum 1.

    Population medicine forum is a seminar-based class during which current topics in population health are presented and discussed. Topics covered include: Outbreak investigation, observational epidemiologic research, risk analysis, spatial analysis, the application of unique diagnostic technologies and epidemiologic modeling.

    CBS 662 Professional Conduct in Biomedical Research 1.

    Plagiarism, authorship, fraud, safety, sexual harassment, IACUC, consulting agreements, serving as an expert witness, contacting elected officials, working with press, human subjects committee, and related topics.

    CBS 675 Supervised Public Health Research 1-9.

    Supervised reserach focused on Public Health. Permission by course instructor required for enrollment.

    CBS 680 MR Special Topics 1-6.

    CBS 681 MR Seminar 1-3.

    CBS 682 Seminar - Poultry Medicine 1-3.

    CBS 683 MR Other Special Topics 1-6.

    CBS 685 Master's Supervised Teaching 1-3.
    Prerequisite: Master's student.

    Teaching experience under the mentorship of faculty who assist the student in planning for the teaching assignment, observe and provide feedback to the student during the teaching assignment, and evaluate the student upon completion of the assignment.

    CBS 693 Master's Supervised Research 1-9.
    Prerequisite: Master's student.

    Instruction in research and research under the mentorship of a member of the Graduate Faculty.

    CBS 695 Master's Thesis Research 1-9.
    Prerequisite: Master's student.

    Thesis research.

    CBS 696 Summer Thesis Research 1.
    Prerequisite: Master's student.

    For graduate students whose programs of work specify no formal course work during a summer session and who will be devoting full time to thesis research.

    CBS 699 Master's Thesis Preparation 1-9.
    Prerequisite: Master's student.

    For students who have completed all credit hour requirements and full-time enrollment for the master's degree and are writing and defending their thesis.

    CBS 711 Applications in Reproductive Physiology 2.

    Students with advanced interests in Theriogenology will meet weekly to discuss a wide range of current topics surrounding animal reproduction, including comparative physiology and endocrinology, reproductive management, reproductive pharmacologic/technologic advances in Theriogenology. Each student will be expected to present 2-3 topics with typed, referenced notes and an oral presentation. All students will be expected to actively participate in group discussions and briefly present a review of one topic-related article from the past 5 years during each lecture.

    CBS 712 Reproductive Management and Disease in Domestic Animals 1.

    Students will meet every other week to review current literature and discuss a wide range of topics surrounding animal reproduction, focused on clinical causes of infertility and their treatments in domestic and non-domestic species. Students will explore 3-5 preassigned questions surrounding a particular topic and prepare an in-depth handout answering those questions prior to arrival. Each student will be expected to actively participate in group discussions.

    CBS 713 Zoonoses and Public Health 3.
    Prerequisite: VPH 580 or equivalent, ST 511 or equivalent.

    Enrollment to graduate veterinarians, MVPH, MPH, or other graduate students. Veterinary students will be considered for enrollment after consultation with the course coordinator.

    CBS 730 Veterinary Histology 3.
    Prerequisite: BCH 451.

    The structure of cells, tissues and organs of domestic animals using light microscopy.

    CBS 731 Applied Veterinary Anatomy I 4.
    Prerequisite: DVM.

    Graduate veterinarian provided with detailed anatomic information relevant to surgical and medical problems in domestic carnivores. Designed for graduate veterinarians in pursuit of advanced training in areas of anatomy, physiology, surgery, radiology and pathology.

    CBS 732 Biological Light and Electron Microscopy:Principles and Practice 5.
    Prerequisite: Graduate standing.

    Principles and applications of various tools for the optical visualization of cells and tissues, with information about how to best ascertain structure-function relationships. Introduction to sample preparation for light and electron microscopy, microtomy, and the theory and utilization of transmission-and scanning electron microscopes, light microscopes and confocal laser scanning microscopes. In addition, cytochemistry, cryotechniques, immunocytochemistry, digital imaging techniques, telemedicine, and silver-based photography techniques will be covered.

    CBS 754 Principles Of Analytical Epidemiology 3.
    Prerequisite: Graduate standing.

    Principles of epidemiology related to investigation of disease involving agent-host-environment concepts. Stress on epidemiological techniques and experimental design. Main focus on descriptive, analytical and experimental epidemiology pertinent to disease etiology and prevention.

    CBS 755 Immunoparasitology 2.
    Prerequisite: MB 751.

    Helminth and protozoal parasite immune evasion and immunomodulation; consequences of parasite-induced immunopathogenesis; learning from failed attempts to develop protective vaccines against protozoa and helminths.

    CBS 760 Molecular Technologies for Epidemiologic Investigation 3.
    Prerequisite: Introductory Epidemiology.

    The course is designed to help students refine their ability to select and interpret molecular diagnostic technologies for epidemiologic disease surveillance and investigation.

    CBS 762 Principles of Pharmacology 3.

    The action of drugs in animals and man including basic principles of drug disposition, pharmacokinetics, drug resistance, and signal transduction. Modification of physiological processes by drugs influencing nervous, renal, cardiovascular, and endocrine systems and the antimicrobic and antineoplastics agents.

    CBS 764 Advances in Gastrointestinal Pathophysiology 3.
    Prerequisite: PHY 503, PHY 504.

    This course will focus on advanced gastrointestinal physiology and the pathophysiology of deseases of relevance to scientsts involved in animal-related research. In particular, the course will cover the pathophysiology of ulceration, infectious diarrhea, ischemia, motility disorders, and inflammatory diseases of the gut. An in-depth review paper will be required based on recent literature rgarding a specific gastrointestinal disease.

    CBS 770 Cell Biology 3.
    Prerequisite: BCH 451 and BIO 183 and (CH 223 or CH 227).

    Advanced cell and organelle structure and function and recent advances in molecular biology. Emphasis on current literature and application of research procedures.

    CBS 771 Cancer Biology 4.
    Prerequisite: CBS 770.

    A comprehensive graduate course focusing on the molecular and cellular bases of cancer. Targets of oncogenic mutations will be discussed as well as their impact on cell proliferation, cell survival, and the invasion of normal tissues by tumorigeniccells. State-of-the-art technologies to detect oncogenic mutations and characterize transformed cells will be discussed as well as therapeutic strategies for the rational treatment of cancer.

    CBS 773 Advanced Developmental Biology 2.

    In-depth coverage of current concepts and new research technologies in developmental biology. Biochemical aspects of germ cell maturation and early development, molecular and genetic regulation of morphogenesis, cellular interaction for organogenesis, hormones and growth factors mediated cellular differentiation and growth, molecular basis of neoplasia apopotises and gene therapy.

    CBS 774 Epidemiology Of Infectious Diseases Of International Importance 3.

    Discussion of infectious diseases and epidemiological principles. Stress on selected enteric, zoonotic, nosocomial diseases of worldwide importance. Consideration of population dynamic techniques related to host-vector-agent.

    CBS 780 Veterinary Production Epidemiology 2.

    Examination of tools, limits, advantages and disadvantages specific to veterinary epidemiology and its execution. Assessment of means of disease prevention and outbreak investigation; mathematical simulation and economics; plus monitoring and evaluation of disease control programs; use of a multiple-species orientation. Application of the above epidemiologic techniques and their roles in assisting producers, practitioners and regulators.

    CBS 782 Marine Mammal Medicine 2.
    Prerequisite: Graduate standing or enrollment in DVM curriculum.

    Discussion of disease issues in free ranging and captive cetaceans, pinnipeds and marine mustelids with emphasis on species found in North American waters. Examination of anatomic, physiologic and behavioral basis of health and population managementand assessment of diagnostic and therapeutic approaches to disease in these species.

    CBS 783 Advanced Immunology 3.
    Prerequisite: MB (IMM) 751.

    In depth study of the basic cellular and molecular mechanisms of immunity, including antigen processing and presentation, T cell development, initiation of the immune response, effector mechanisms, and immunological memory. The course is designed for advanced graduate students who wish to focus on the current concepts in immunology.

    CBS 785 Advanced and Molecular Pharmacology 2.
    Prerequisite: CBS 762.

    A course for graduate students providing a comprehensive investigation of current topics in Pharmacology with an emphasis on molecular and cellular approaches in lecture and discussion formats. Faculty will introduce each subject area and students will read recent articles, present seminars, and write professional-grade papers.

    CBS 787 Pharmacokinetics 3.
    Prerequisite: CBS 560, working knowledge of calculus.

    Mathematical models to describe disposition of drugs and toxic chemicals in the animal body. Areas including classic compartmental and nonlinear models as well as physiological approaches. Discussion of application of these techniques to toxicologicstudies.

    CBS 790 Special Topics in Clinical Pathology 1-6.
    Prerequisite: Those holding the DVM degree.

    New, fundamental and in-depth understanding of selected topics in clinical pathology (blood coagulation, acid-base balance, hematology, cytology, and clinical chemistry). A new topic selected each semester. Students read pertinent current journal articles and references and lead weekly discussion sessions. Stress upon clinical spplication of this information.

    CBS 795 Special Topics in Comparative Biomedical Sciences 1-6.
    Prerequisite: Graduate Students, DVM or equivalent degree.

    Special Topics in Comparative Biomedical Sciences.

    CBS 800 CBS Seminar 1.

    Presentation and discussions on ongoing research and current topics in biomedical sciences.

    CBS 802 Seminar In Biology Of Reproduction 2.
    Prerequisite: ANS(PHY) 702.

    Current topics in animal reproduction presented by reproductive physiologists from various Research Triangle institutions. Student presentations of research projects or library projects in area of animal reproduction.

    CBS 803 Seminar in Surgical Pathology 1.
    Prerequisite: Those holding the DVM or equivalent degree.

    Description and interpretation of microscopic changes in tissues from diseased domestic and laboratory animals. Students attend and participate in a one-hour weekly seminar where microscopic lesions described, interpreted and discussed.

    CBS 804 Seminar in Necropsy Pathology 1.
    Prerequisite: Those holding the DVM or equivalent degree.

    Description and interpretation of gross changes in tissues from diseased domestic animals. Students attend daily (M-F) 15-to 30-minute review of necropsy lesions presented by a member of the graduate staff.

    CBS 807 Seminar in Veterinary Microbiology/Immunology 1.

    Presentation of ongoing research and current topics in microbiology.

    CBS 810 Special Topics 1-6.
    Prerequisite: Senior standing or Graduate standing.

    Designed to present new or special subject matter within the scope of pathology, veterinary microbiology, morphology or pharmacology. The studies may include independent investigations, seminars and/or formal lectures.

    CBS 812 Special Topics Pathology 1-6.
    Prerequisite: Those holding the DVM degree.

    Specific topics of study assigned in various laboratories involved in veterinary microbiology investigation. Students conduct in-dept studies of assigned problem areas.

    CBS 813 Special Topics Laboratory Pharmology 1-6.
    Prerequisite: Graduate standing.

    Involvement in practical participation in the normal research activities of different laboratories working in pharmacological research. Students pursue a semi-independent project.

    CBS 815 Advanced Topics in Virology 1.
    Prerequisite: VMM 924 or MB 718.

    Selected topics of current interest in virology. A new topic selected each time course is offered to keep the advanced gradute students up to date on the most recent developments in these fields.

    CBS 816 Advanced Topics In Immunology 1.
    Prerequisite: MB 751.

    Selected topics of current interest in immunology. A different topic will be covered each semester to focus on the most recent developments in the field.

    CBS 817 Advanced Topics In Zoological Medicine I 2.
    Prerequisite: Graduate standing or enrollment in DVM curriculum.

    Selected topics of current interest in clinical zoological medicine focused on marine mammals, fish, reptiles, amphibians, waterfowl, ratites, raptors and medical issues in free-ranging wildlife. Review of current clinical and basic science literature, student-lead discussion sessions and participation in faculty-lead discussions.

    CBS 818 Advanced Topics in Zoological Medicine 2.
    Prerequisite: Graduate standing or enrollment in DVM curriculum.

    This course provides breadth and depth of knowledge in zoological medicine to prepare Zoological Medicine residents to pass American College of Zoological Medicine (ACZM) boards. Veterinary students are exposed to more in depth information related to zoological medicine than covered in their core curriculum. Each Fall (CBS 817) and Spring (CBS 818) semesters, different aspects of zoological medicine are covered. Topics rotate every 3 years so that all major groups of animals within the sub-groups, avian, aquatic, herptile, wildlife, and zoo are addressed.

    CBS 820 Special Problems 1-6.

    CBS 860 Techniques in Pharmacological Research 2.
    Prerequisite: BCH 452B or CH 315 and Graduate standing.

    Theory and applications of modern scientific instrumentation to analysis of tissues, body fluids and drugs in pharmacological research. Discussion of appropriate aspects of the pharmacological use of spectroscopy, microscopy, chromatography, electrophoresis, radioisotope usage and centrifugation.

    CBS 885 Doctoral Supervised Teaching 1-3.
    Prerequisite: Doctoral student.

    Teaching experience under the mentorship of faculty who assist the student in planning for the teaching assignment, observe and provide feedback to the student during the teaching assignment, and evaluate the student upon completion of the assignment.

    CBS 886 One Health: From Philosophy to Practice 2.

    Graduate/professional seminar (with team project) addressing intersections of veterinary medicine, human medicine, and environmental health. Co-listed at UNC CH Gillings School of Global Public Health and Duke University School of Medicine. Includes participants from these three institutions, plus related private-sector members, non-governmental organizations, and government professionals. Its purpose is to facilitate understanding of one health as a system of systems, and promote cross-campus and cross-discipline interactions. Weekly evening course held at NC Biotechnology Center, RTP. Requires graduate student standing at NCSU or professional student standing within the College of Veterinary Medicine. Limit: 15 students per university.

    CBS 890 Doctoral Preliminary Examination 1-9.
    Prerequisite: Doctoral student.

    For students who are preparing for and taking written and/or oral preliminary exams.

    CBS 893 Doctoral Supervised Research 1-9.
    Prerequisite: Doctoral student.

    Instruction in research and research under the mentorship of a member of the Graduate Faculty.

    CBS 895 Doctoral Dissertation Research 1-9.
    Prerequisite: Doctoral student.

    Dissertation research.

    CBS 896 Summer Dissertation Research 1.
    Prerequisite: Doctoral student.

    For graduate students whose programs of work specify no formal course work during a summer session and who will be devoting full time to thesis research.

    CBS 899 Doctoral Dissertation Preparation 1-9.
    Prerequisite: Doctoral student.

    For students who have completed all credit hour, full-time enrollment, preliminary examination, and residency requirements for the doctoral degree, and are writing and defending their dissertations.