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Toxicology (TOX)

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  • TOX - Toxicology Courses

    TOX 201 Poisons, People and the Environment 3.

    Introduction to the fascinating world of chemical poisons including their many and varied effects on people as well as the environment. Learn how and why poisons have played an important role in history, how to critically evaluate the chemical risk information reported in the media, and the underlying principles of "the basic science of poisons.".

    TOX 401 Principles of Toxicology 4.
    Prerequisite: CH 220 or CH 221 or CH 225; BIO 181 or ZO 160.

    Introduce students to the basic principles of toxicology. Will cover the history and scope of the field; absorption, distribution, metabolism and elimination of toxicants; types and mechanisms of toxic action; carcinogenesis; environmental toxicology as well as human and ecological risk assessment.

    TOX 415 Environmental Toxicology and Chemistry 4.
    Prerequisite: CH 220 or CH 221 or CH 225; BIO 181 or ZO 160 recommended.

    Environmental toxicology and chemistry including the sources, fate, and effects of chemicals in the environment. Emphasis on contemporary problems in human health and the environment.

    TOX 501 Principles of Toxicology 4.
    Prerequisite: (CH 220 or CH 221 or CH 225) and (BIO 181 or ZO 160).

    Introduce students to the basic principles of toxicology. Will cover the history and scope of the field; absorption, distribution, metabolism and elimination of toxicants; types and mechanisms of toxic action; carcinogenesis; environmental toxicology as well as human and ecological risk assessment.

    TOX 515 Environmental Toxicology 4.
    Prerequisite: Two years of biology.

    Evaluation of the nature, distribution and significance of microchemical contamination. Emphasis on current, relevant problems.

    TOX 595 Special Topics 1-6.

    TOX 601 Toxicology Seminar 1.
    Prerequisite: Graduate standing.

    TOX 620 Special Problems 1-6.
    Prerequisite: Graduate standing.

    Topics include responsibility in science, environmental fate of chemicals, developmental toxicology, lab rotations, journal club and wildlife toxicology.

    TOX 660 Free Radicals In Toxicology 1.
    Prerequisite: BCH 451 and TOX 710.

    Introduction to the field of free radicals and their role in toxicology and health; chemical and physical properties of partially reduced oxygen intermediates and the natural biological defense mechanisms.

    TOX 688 Non-Thesis Masters Continuous Registration - Half Time Registration 1.
    Prerequisite: Master's student.

    For students in non-thesis master's programs who have completed all credit hour requirements for their degree but need to maintain half-time continuous registration to complete incomplete grades, projects, final master's exam, etc.

    TOX 689 Non-Thesis Master Continuous Registration - Full Time Registration 3.
    Prerequisite: Master's student.

    For students in non-thesis master's programs who have completed all credit hour requirements for their degree but need to maintain full-time continuous registration to complete incomplete grades, projects, final master's exam, etc. Students may register for this course a maximum of one semester.

    TOX 690 Master's Exam 1-9.
    Prerequisite: Master's student.

    For students in non thesis master's programs who have completed all other requirements of the degree except preparing for and taking the final master's exam.

    TOX 693 Master's Supervised Research 1-9.
    Prerequisite: Master's student.

    Instruction in research and research under the mentorship of a member of the Graduate Faculty.

    TOX 695 Master's Thesis Research 1-9.
    Prerequisite: Master's student.

    Thesis research.

    TOX 696 Summer Thesis Research 1.
    Prerequisite: Master's student.

    For graduate students whose programs of work specify no formal course work during a summer session and who will be devoting full time to thesis research.

    TOX 699 Master's Thesis Preparation 1-9.
    Prerequisite: Master's student.

    For students who have completed all credit hour requirements and full-time enrollment for the master's degree and are writing and defending their theses.

    TOX 701 Fundamentals of Toxicology 3.
    Prerequisite: BCH 451, Senior standing or Graduate standing.

    The basis of toxic action at cellular and molecular levels covering the absorption, distribution, elimination and metabolism of toxicants; toxic action (acute toxicity, carcinogenesis, mutagenesis, organ toxicity, etc.); chemical classes of toxicants; and toxicity testing.

    TOX 704 Chemical Risk Assessment 1.
    Prerequisite: TOX 701, a ST course.

    Concepts and vocabulary of risk assessment. Risk assessment models and techniques used in cancer and non-cancer risk assessment and strategies for successful risk communications. Case studies of risk assessment and issues of current interest. Utilization of background in toxicology and statistics to examine a critical end-point in toxicological science, the quantitative risk assessment.

    TOX 710 Molecular and Biochemical Toxicology 3.
    Prerequisite: BCH 451; TOX 701.

    Fundamental understanding of biochemical, molecular and cellular mechanisms through which xenobiotics alter cellular homeostasis, produce toxicity and alter organ function. Current biochemical, molecular and cellular experimental approaches for study of biochemical mechanisms of toxicity.

    TOX 715 Environmental Toxicology 3.
    Prerequisite: Two years of biology.

    Evaluation of fundamental processes relating fate and effects of chemicals in the environment. Emphasis on effects of pollutants on non-human species, environmental risk assessment and historically relevant incidents of environmental contaminants.

    TOX 725 Pesticide Chemistry 1.
    Prerequisite: (CH 201 or CH 203) and (CH 221 or CH 225).

    Chemical properties of pesticides including hydration and solvation, ionization, volatilization, lipophilicity, molecular structure and size, and reactivity and classification according to chemical description, mode of action or ionizability. Taughtduring the first 5 weeks of semester. Drop date is last day of 3rd week of the minicourse.

    TOX 727 Pesticide Behavior and Fate In the Environment 2.
    Prerequisite: CS(HS,SSC,TOX) 725, SSC 200.

    Sorption/desorption, soil reactivity, movement, volatilization, bioavailability, degradation and stability of pesticides in the environment. Taught during the last 10 weeks of semester. Drop date is last day of 3rd week of the minicourse.

    TOX 771 Cancer Biology 4.
    Prerequisite: CBS 770.

    A comprehensive graduate course focusing on the molecular and cellular bases of cancer. Targets of oncogenic mutations will be discussed as well as their impact on cell proliferation, cell survival, and the invasion of normal tissues by tumorigeniccells. State-of-the-art technologies to detect oncogenic mutations and characterize transformed cells will be discussed as well as therapeutic strategies for the rational treatment of cancer.

    TOX 795 Special Topics in Toxicology 1-6.

    TOX 801 Toxicology Seminar 1.
    Prerequisite: Graduate standing.

    TOX 820 Special Problems In Toxicology 1-6.
    Prerequisite: Graduate standing.

    Topics include responsibility in science, environmental fate of chemicals, developmental toxicology, lab rotations, Journal Club, and wildlife toxicology.

    TOX 860 Free Radicals in Toxicology 1.
    Prerequisite: BCH 451 and TOX 710.

    Introduction to the field of free radicals and their role in toxicology and health; chemical and physical properties of partially reduced oxygen intermediates and the natural biological defense mechanisms.

    TOX 890 Doctoral Preliminary Examination 1-9.
    Prerequisite: Doctoral student.

    For students who are preparing for and taking written and/or oral preliminary exams.

    TOX 893 Doctoral Supervised Research 1-9.
    Prerequisite: Doctoral student.

    Instruction in research and research under the mentorship of a member of the Graduate Faculty.

    TOX 895 Doctoral Dissertation Research 1-9.
    Prerequisite: Doctoral student.

    Dissertation research.

    TOX 896 Summer Dissertation Research 1.
    Prerequisite: Doctoral student.

    For graduate students whose programs of work specify no formal course work during a summer session and who will be devoting full time to thesis research.

    TOX 899 Doctoral Dissertation Preparation 1-9.
    Prerequisite: Doctoral student.

    For students who have completed all credit hour, full-time enrollment, preliminary examination, and residency requirements for the doctoral degree, and are writing and defending their dissertations.