University Catalog 2025-2026

Chemical Engineering (BS): Biomanufacturing Sciences Concentration

The Biomanufacturing Sciences Concentration provides students with the knowledge base and hands-on skills that prepare them to quickly contribute to a biomanufacturing operation. Pharmaceuticals, vaccines, enzymes, and bio-fuels are example products. Students completing this concentration also fulfill the requirements for a Minor in Biomanufacturing.

Plan Requirements

Plan of Study Grid
First Year
Fall SemesterHours
CH 101
Chemistry - A Molecular Science 1
or General Chemistry I for Students in Chemical Sciences
3
CH 102
General Chemistry Laboratory 1
or General Chemistry Laboratory I for Students in Chemical Sciences
1
E 101 Introduction to Engineering & Problem Solving 2 1
E 115 Introduction to Computing Environments 1
MA 141 Calculus I 1 4
ENG 101 Academic Writing and Research 2 4
 Hours14
Spring Semester
CH 201
Chemistry - A Quantitative Science 2
or General Chemistry II for Students in Chemical Sciences
3
CH 202
Quantitative Chemistry Laboratory 2
or General Chemistry Laboratory II for Students in Chemical Sciences
1
MA 241 Calculus II 4
PY 205
PY 206
Physics for Engineers and Scientists I
and Physics for Engineers and Scientists I Laboratory 1
4
Select one of the following Economics Courses: 3
Introduction to Agricultural & Resource Economics
Introduction to Agricultural & Resource Economics
Principles of Microeconomics
Fundamentals of Economics
E 102 Engineering in the 21st Century 2
 Hours17
Second Year
Fall Semester
CH 221
Organic Chemistry I 2
or Organic Chemistry I for Students in Chemical Sciences
3
CH 222
Organic Chemistry I Lab 2
or Organic Chemistry Laboratory I for Students in Chemical Sciences
1
CHE 205 Chemical Process Principles 2 4
MA 242 Calculus III 2 4
PY 208
PY 209
Physics for Engineers and Scientists II
and Physics for Engineers and Scientists II Laboratory
4
BEC 220 Introduction to Drug Development and Careers in Biomanufacturing 1
 Hours17
Spring Semester
CH 223
Organic Chemistry II
or Organic Chemistry II for Students in Chemical Sciences
3
CH 224
Organic Chemistry II Lab
or Organic Chemistry Laboratory II for Students in Chemical Sciences
1
CHE 225 Introduction to Chemical Engineering Analysis 2 3
MA 341 Applied Differential Equations I 2 3
BIO 183 Introductory Biology: Cellular and Molecular Biology 4
 Hours14
Third Year
Fall Semester
CHE 311 Transport Processes I 2 3
CHE 315 Chemical Process Thermodynamics 2 3
BCH 451 Principles of Biochemistry 4
BEC 425 Molecular Biology for Biomanufacturing 2
BEC 463
Fermentation of Recombinant Microorganisms
or Principles and Applications of Bioseparations
2
 Hours14
Spring Semester
CHE 312 Transport Processes II 3
CHE 316 Thermodynamics of Chemical and Phase Equilibria 3
BEC 330
Principles and Applications of Bioseparations
or Fermentation of Recombinant Microorganisms
2
Biomanufacturing Elective 2
 Hours10
Fourth Year
Fall Semester
CHE 446 Design and Analysis of Chemical Reactors 3
CHE 450
Chemical Engineering Design I
or Engineering Entrepreneurship Senior Design I
3
CHE 395 Professional Development Seminar 1
Select one of the following sequences: 4
cGMP Fermentation Operations
and Upstream Biomanufacturing Laboratory
cGMP Downstream Operations
and Introduction to Downstream Process Development
 Hours11
Spring Semester
CHE 448 Bioreactor Design 2
CHE 435 Process Systems Analysis and Control 3
CHE 451
Chemical Engineering Design II
or Engineering Entrepreneurship Senior Design II
3
Biomanufacturing Elective 2
Bioethics Elective 3
 Hours13
 Total Hours110
1

A grade of C or higher is required.

2

A grade of C- or higher is required.

GEP Courses
GEP Humanities6
GEP Social Sciences3
GEP Health and Exercise Studies2
GEP Elective3
GEP Global Knowledge (verify requirement)
GEP Foundations of American Democracy (verify requirement)
World Language Proficiency (verify requirement)
Free Electives
Free Electives (12 Hr S/U Lmt) 13
Total Hours17
1

Students should consult their academic advisors to determine which courses fill this requirement.

Biomanufacturing Electives

BBS 325Introduction to Brewing Science and Technology3
BBS 326Brewing Practices and Analyses3
BBS 427Brewing Equipment, Controls and Operations3
BEC 426Upstream Biomanufacturing Laboratory2
BEC 436Introduction to Downstream Process Development2
BEC 445Cell Line Development for Biomanufacturing2
or BEC 545 Cell Line Development for Biomanufacturing
BEC 462Fundamentals of Bio-Nanotechnology3
BEC 472Drug Delivery - Theory and Modern Practices3
BEC 475Global Regulatory Affairs for Medical Products3
or BEC 575 Global Regulatory Affairs for Medical Products
BEC 480cGMP Fermentation Operations2
or BEC 580 cGMP Fermentation Operations
BEC 485cGMP Downstream Operations2
or BEC 585 cGMP Downstream Operations
BEC 488Animal Cell Culture Engineering2
BEC 495Special Topics in Biomanufacturing1-4
BEC 497Biomanufacturing Research Projects1-3
BEC 545Cell Line Development for Biomanufacturing2
BEC 585cGMP Downstream Operations2
BEC 526Upstream Biomanufacturing Laboratory2
BEC 562Fundamentals of Bio-Nanotechnology3
BEC 572Drug Delivery - Theory and Modern Practices3
BEC 575Global Regulatory Affairs for Medical Products3
BEC 580cGMP Fermentation Operations2
BEC 588Animal Cell Culture Engineering2
BEC 595Special Topics in Biomanufacturing1-6
BME 483Tissue Engineering Technologies2
CHE 452Biomolecular Engineering2
CHE 552Biomolecular Engineering2

Bioethics Electives 

CS 224Seeds, Biotechnology and Societies3
IDS 201Environmental Ethics3
IDS 303Humans and the Environment3
NR 303Humans and the Environment3
PHI 325Bio-Medical Ethics3
STS 302Contemporary Science, Technology and Human Values3
STS 304Ethical Dimensions of Progress3
STS 325Bio-Medical Ethics3

Semester Sequence

This is a sample.

Plan of Study Grid
First Year
Fall SemesterHours
CH 101
Chemistry - A Molecular Science 1
or General Chemistry I for Students in Chemical Sciences
3
CH 102
General Chemistry Laboratory 1
or General Chemistry Laboratory I for Students in Chemical Sciences
1
E 101 Introduction to Engineering & Problem Solving 1 1
E 115 Introduction to Computing Environments 1
ENG 101 Academic Writing and Research 1 4
MA 141 Calculus I 4
GEP Health and Exercise Studies 1
 Hours15
Spring Semester
CH 201
Chemistry - A Quantitative Science 2
or General Chemistry II for Students in Chemical Sciences
3
CH 202
Quantitative Chemistry Laboratory
or General Chemistry Laboratory II for Students in Chemical Sciences
1
MA 241 Calculus II 1 4
PY 205 Physics for Engineers and Scientists I 1 3
PY 206 Physics for Engineers and Scientists I Laboratory 1 1
E 102 Engineering in the 21st Century 2
GEP Health and Exercise Studies 1
 Hours15
Second Year
Fall Semester
BEC 220 Introduction to Drug Development and Careers in Biomanufacturing 1
CH 221
Organic Chemistry I 2
or Organic Chemistry I for Students in Chemical Sciences
3
CH 222
Organic Chemistry I Lab
or Organic Chemistry Laboratory I for Students in Chemical Sciences
1
CHE 205 Chemical Process Principles 4
MA 242 Calculus III 4
PY 208 Physics for Engineers and Scientists II 3
PY 209 Physics for Engineers and Scientists II Laboratory 1
 Hours17
Spring Semester
BIO 183 Introductory Biology: Cellular and Molecular Biology 4
CH 223
Organic Chemistry II
or Organic Chemistry II for Students in Chemical Sciences
3
CH 224
Organic Chemistry II Lab
or Organic Chemistry Laboratory II for Students in Chemical Sciences
1
CHE 225 Introduction to Chemical Engineering Analysis 2 3
MA 341 Applied Differential Equations I 2 3
Select one of the following: 3
Fundamentals of Economics
Principles of Microeconomics
Introduction to Agricultural & Resource Economics
 Hours17
Third Year
Fall Semester
BCH 451 Principles of Biochemistry 4
BEC 425 Molecular Biology for Biomanufacturing 2
BEC 463
Fermentation of Recombinant Microorganisms
or Principles and Applications of Bioseparations
2
CHE 311 Transport Processes I 1 3
CHE 315 Chemical Process Thermodynamics 1 3
GEP Requirement 3
 Hours17
Spring Semester
BEC 330
Principles and Applications of Bioseparations
or Fermentation of Recombinant Microorganisms
2
CHE 312 Transport Processes II 3
CHE 316 Thermodynamics of Chemical and Phase Equilibria (Bioethics Elective ) 3
Free Elective 3
Biomanufacturing Elective 2
GEP Requirement 3
 Hours16
Fourth Year
Fall Semester
CHE 446 Design and Analysis of Chemical Reactors 3
CHE 450
Chemical Engineering Design I
or Engineering Entrepreneurship Senior Design I
3
CHE 395 Professional Development Seminar 1
GEP Requirement 3
Select one of the following sequences: 4
cGMP Fermentation Operations
and Upstream Biomanufacturing Laboratory
Introduction to Downstream Process Development
and cGMP Downstream Operations
 Hours14
Spring Semester
Biomanufacturing Elective 2
CHE 448 Bioreactor Design 2
CHE 435 Process Systems Analysis and Control 3
CHE 451
Chemical Engineering Design II
or Engineering Entrepreneurship Senior Design II
3
Bioethics Elective 3
GEP Requirement 3
 Hours16
 Total Hours127
1

A grade of C or higher is required.

2

A grade of C- or higher is required.

Career Opportunities

Careers in chemical engineering are sometimes exciting, always demanding, and ultimately provide a sense of accomplishment and achievement. Graduates find employment in sub-disciplines such as production, technical service, sales, management and administration; research and development; and consulting and teaching. Students desiring careers in teaching, research, or consulting are encouraged to continue their education and pursue a graduate degree (consult the Graduate Catalog). The undergraduate curriculum also provides strong preparation for graduate study in a wide range of professional specialties, and chemical engineering graduates often pursue careers in the medical sciences, business management, and law.

Career Titles

  • Agricultural Engineer
  • Automotive Engineer
  • Biochemist
  • Biomedical Engineer
  • Chemical Engineer
  • Chemist
  • Dairy Technologist
  • Electronics Engineer
  • Engineering Professor
  • Environmental Engineer
  • Fire Prevention Engineer
  • Industrial Air Pollution Analyst
  • Industrial Waste Inspector
  • Laboratory Tester
  • Materials Engineer
  • Materials Scientist
  • Nanosystems Engineers
  • Non-Destructive Testing Specialists
  • Nuclear Engineer
  • Nuclear Fuels Research Engineer
  • Occupational Safety & Health Inspector
  • Perfumer
  • Petroleum Engineer
  • Physicist
  • Physics Professor
  • Product Safety Engineer
  • Quality Control Managers
  • Radiation Protection Engineer
  • Safety Inspector
  • Sales Engineers
  • Sales Representative (Chemicals & Drugs)
  • Soil Engineer
  • Solar Energy Systems Engineers
  • Sustainability Specialists
  • Toxicologist
  • Water/Wastewater Engineers

Learn More About Careers

NCcareers.org
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Occupational Outlook Handbook
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Career One Stop Videos
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Focus 2 Career Assessment (NC State student email address required)
This career, major and education planning system is available to current NC State students to learn about how your values, interests, competencies, and personality fit into the NC State majors and your future career. An NC State email address is required to create an account. Make an appointment with your career counselor to discuss the results.

Focus 2 Apply Assessment (Available to prospective students)
A career assessment tool designed to support prospective students in exploring and choosing the right major and career path based on your unique personality, interests, skills and values. Get started with Focus 2 Apply and see how it can guide your journey at NC State.

American Institute of Chemical Engineers
American Chemical Society
American Oil Chemists’ Society
National Society of Professional Engineers