University Catalog 2024-2025

Biochemistry (BS)

The Bachelor of Science degree in Biochemistry

Biochemistry is an interdisciplinary science focused on chemical processes that occur in living systems. The mission of the Biochemistry undergraduate program is to prepare and inspire students for the discovery and dissemination of knowledge to the greater life sciences community through research and instruction. The faculty believe in a balance of interdependent formal classroom instruction with innovative laboratory training and experience in inquiry-based research methods. Classroom and lab training emphasize chemistry, physics, and biology of metabolism, molecular biology, macromolecular structure, function and synthesis. The ultimate goal is to infuse each student with sufficient breadth and depth of understanding that they are conversant in the rigors of life at the molecular level, and capable of contributing to a wide variety of future career paths that require detailed understanding of physical and chemical principles in living systems. Our program is accredited by the American Society for Biochemistry and Molecular Biology.

Accelerated Bachelors/Masters programs in Biochemistry and Biochemistry/Biomanufacturing

Advanced, academically qualified undergraduate students have the opportunity to participate in the Accelerated Bachelor's/Master's (ABM) programs in Biochemistry or in Biochemistry & Biomanufacturing. These programs allow students to earn both the BS and the MS degrees in Biochemistry or the combined disciplines within five years.

For more information about Biochemistry, visit our program website

Program Requirements

Orientation
BCH 103Introduction to Biochemistry 11
or ALS 103 Freshman Transitions and Diversity in Agriculture & Life Sciences
or ALS 303 Transfer Transitions and Diversity in Agriculture & Life Sciences
or LSC 103 Exploring Opportunities in the Life Sciences
English & Advanced Writing
ENG 101Academic Writing and Research (C- or better) 14
ENG 331Communication for Engineering and Technology 13
or ENG 333 Communication for Science and Research
Mathematical Science & Physics
Choose one of the following Math sequences:12
Calculus I 1,2
Calculus II 1,2
Calculus III 1,2
OR
Calculus for Life and Management Sciences A 1,2
Calculus for Life and Management Sciences B 1,2
Introduction to Statistics 1,2
or ST 380
Advised Elective MA, ST or CSC 1,2,5
PY 205
PY 206
Physics for Engineers and Scientists I
and Physics for Engineers and Scientists I Laboratory 1,3
4
or PY 211 College Physics I
PY 208
PY 209
Physics for Engineers and Scientists II
and Physics for Engineers and Scientists II Laboratory 1,3
4
or PY 212 College Physics II
Chemistry/Lab Analysis
CH 101
CH 102
Chemistry - A Molecular Science
and General Chemistry Laboratory 1,8
4
CH 201
CH 202
Chemistry - A Quantitative Science
and Quantitative Chemistry Laboratory 1,8
4
CH 221
CH 222
Organic Chemistry I
and Organic Chemistry I Lab 1,8
4
CH 223
CH 224
Organic Chemistry II
and Organic Chemistry II Lab 1,8
4
Select one of the following Physical Chemistry sequences:6
Introductory Physical Chemistry 1,7
Physical Biochemistry
Sciences Advised Elective 1,7
OR
Physical Chemistry I
and Physical Chemistry II 1,7
Laboratory Analysis Elective 1,63
Life Sciences
LSC 101Critical and Creative Thinking in the Life Sciences2
BIO 181Introductory Biology: Ecology, Evolution, and Biodiversity 14
BIO 183Introductory Biology: Cellular and Molecular Biology 14
Advised Elective 1,43
BCH 451Principles of Biochemistry 14
BCH 453Biochemistry of Gene Expression 13
or BCH 553 Biochemistry of Gene Expression
BCH 455Proteins and Molecular Mechanisms 13
or BCH 555 Proteins and Molecular Mechanisms
Biochemistry Laboratory Elective5-6
Introductory Biochemistry Laboratory 1
and one of the following:
Advanced Biochemistry Laboratory 1,6
Honors Research or Teaching II 1
External Learning Experience 1
Special Problems in Biochemistry 1
MB 351General Microbiology 13
MB 352General Microbiology Laboratory 11
or MB 354 Inquiry-Guided Microbiology Lab
GN 311Principles of Genetics 14
Cell Biology/Physiology: Select one of the following:3
Principles of Human Anatomy & Physiology (A): Nervous, Skeletal, Muscular, & Digestive Systems 1
Principles of Human Anatomy & Physiology (B): Endocrine, Cardiovascular, Respiratory & Renal Systems 1
Cell Biology 1
Plant Physiology 1
GEP Courses
GEP Humanities6
GEP Social Sciences6
GEP Health and Exercise Studies2
GEP US Diversity, Equity, and Inclusion3
GEP Interdisciplinary Perspectives3
GEP Global Knowledge (verify requirement)
Foreign Language Proficiency (verify requirement)
Free Electives
Free Electives (12 Hr S/U Lmt) 28
Total Hours120-121
1

A grade of C- or higher is required.

2

There are two sequences for mathematics:  MA 131, MA 231, ST 311 [ST 380], and a math/ST/CSC elective OR MA 141, MA 241, and MA 242.  The three semester sequence (MA 141,241 and 242) is a prerequisite for PY 205 and 208 and for CH 431 and 433 (CH 431/433 also requires MA 341). This sequence is recommended for those students who plan on graduate studies in Biophysics or a related specialty in Biochemistry, and is required for Biochemistry Honors Option 1. If a student elects to start with MA 141, the sequence of 241 and 242 should be taken. If a student elects to start with MA 131 and MA 231, the sequence of ST 311 [ST 380] and a math/ST/CSC elective should be taken. ST 311 or ST 380 is not a substitute for MA 242.

3

The calculus based physics sequence (PY 205 and 208) is recommended for those students who plan on graduate studies in Biophysics or a related specialty in Biochemistry; and is required for Biochemistry Honors Option 1. If a student chooses PY 205, PY 208 should be taken. 

4

This course is an advised elective in the life sciences.  BIO 240 or BIO 245 is recommended for those students who are interested in applying to the health related professions. This requirement can also be satisfied by an advised elective from upper level life science courses (life science course, 200 level or above; verify with advisor).

5

If a student has chosen the Math sequence of MA 131, MA 231, and ST 311, another course (200 level or above; verify with advisor) in computer science, mathematics or statistics must be chosen.  

6

If BCH 454 is not selected as an option for the Biochemistry Laboratory elective it may be used as an option for the Laboratory Analysis elective.

7

The two semester Physical Chemistry course sequence (CH 431 and 433) is recommended for those students who plan on graduate studies in Biophysics or a related specialty in Biochemistry, and is required for Biochemistry Honors Option 1.  If CH 431 is chosen, CH 433 must be taken. If CH 331 or BCH 330 is chosen, a student must choose an advised elective from upper level courses offered in the sciences, math or computer science (200 level or above; verify with advisor).

8

The corresponding courses for chemistry majors may be substituted (CH 103,104 for CH 101,102; CH 203,204 for CH 201,202; CH 225,226 for CH 221,222; CH 227,228 for CH 223,224).

Laboratory Analysis Elective

BCH 454Advanced Biochemistry Laboratory4
BEC 463/563Fermentation of Recombinant Microorganisms2
BIT 463Fermentation of Recombinant Microorganisms2
BIT 464Protein Purification2
BIT 465Real-time PCR Techniques2
BIT 466Animal Cell Culture Techniques2
BIT 467PCR and DNA Fingerprinting2
BIT 471RNA Interference and Model Organisms2
BIT 473Protein Interactions2
BIT 474Plant Genetic Engineering2
BIT 476Applied Bioinformatics2
BIT 477Metagenomics2
BIT 479High-Throughput Discovery2
BIT 480Yeast Metabolic Engineering2
BIT 481Plant Tissue Culture and Transformation2
BIT 502Biotechnology Networking and Professional Development1
BIT 563Fermentation of Recombinant Microorganisms2
BIT 564Protein Purification2
BIT 565Real-time PCR Techniques2
BIT 566Animal Cell Culture Techniques2
BIT 567PCR and DNA Fingerprinting2
BIT 571RNA Interference and Model Organisms2
BIT 573Protein Interactions2
BIT 574Plant Genetic Engineering2
BIT 577Metagenomics2
BIT 579High-Throughput Discovery2
BIT 580Yeast Metabolic Engineering2
CH 315Quantitative Analysis3
CH 316Quantitative Analysis Laboratory1
CHE 463Fermentation of Recombinant Microorganisms2
CHE 563Fermentation of Recombinant Microorganisms2
PB 481Plant Tissue Culture and Transformation2
PO 466Animal Cell Culture Techniques2
PO 566Animal Cell Culture Techniques2

Semester Sequence

This is a sample.

Plan of Study Grid
First Year
Fall SemesterHours
BCH 103 Introduction to Biochemistry 1
BIO 181 Introductory Biology: Ecology, Evolution, and Biodiversity 1 4
CH 101 Chemistry - A Molecular Science 1,8 3
CH 102 General Chemistry Laboratory 1,8 1
GEP Health and Exercise Studies 1
LSC 101 Critical and Creative Thinking in the Life Sciences 2
MA 141
Calculus I 1,2
or Calculus for Life and Management Sciences A
3-4
 Hours15
Spring Semester
BIO 183 Introductory Biology: Cellular and Molecular Biology 1 4
CH 201 Chemistry - A Quantitative Science 1,8 3
CH 202 Quantitative Chemistry Laboratory 1,8 1
ENG 101 Academic Writing and Research 4
MA 241
Calculus II 1,2
or Calculus for Life and Management Sciences B
3-4
 Hours15
Second Year
Fall Semester
CH 221 Organic Chemistry I 1,8 3
CH 222 Organic Chemistry I Lab 1,8 1
Select one of the following:
MA 242
or ST 311
or ST 380
Calculus III 1,2
or Introduction to Statistics
or
4
Select one of the following: 4
College Physics I 1,3
Physics for Engineers and Scientists I
and Physics for Engineers and Scientists I Laboratory 1,3
Life Science Elective 1,4 3-4
GEP Health and Exercise Studies 1
 Hours16
Spring Semester
CH 223 Organic Chemistry II 1,8 3
CH 224 Organic Chemistry II Lab 1,8 1
MB 351 General Microbiology 1 3
MB 352
General Microbiology Laboratory 1
or Inquiry-Guided Microbiology Lab
1
Select one of the following: 4
College Physics II 1,3
Physics for Engineers and Scientists II
and Physics for Engineers and Scientists II Laboratory 1,3
Select one of the following: 3
Computer Elective 1,5
Math Elective 1,5
Statistics Elective 1,5
Free Elective
 Hours15
Third Year
Fall Semester
BCH 451 Principles of Biochemistry 1 4
BCH 452 Introductory Biochemistry Laboratory 1 2
GN 311 Principles of Genetics 1 4
GEP Humanities 3
GEP Social Sciences 3
 Hours16
Spring Semester
BCH 453 Biochemistry of Gene Expression 1 3
Select one of the following: 1 3-4
Advanced Biochemistry Laboratory 1,6
Research Elective (BCH 492, BCH 493, ALS 499) 1
ENG 331
Communication for Engineering and Technology
or Communication for Science and Research
3
GEP Social Sciences 3
GEP Interdisciplinary Perspectives 3
 Hours15
Fourth Year
Fall Semester
Cell Biology or Physiology Elective 1 3
Select one of the following: 3-4
Physical Chemistry I 1,7
or Introductory Physical Chemistry
or Physical Biochemistry
Free Elective 3
GEP Humanities 6
 Hours15-16
Spring Semester
Select one of the following: 3-4
Physical Chemistry II 1,7
Advised Elective 1,7
BCH 455 Proteins and Molecular Mechanisms 1 3
GEP US Diversity, Equity, and Inclusion 3
Lab Analysis 1,6 3-4
Free Elective 2
 Hours14
 Total Hours121-122
1

A grade of C- or higher is required.

2

There are two sequences for mathematics:  MA 131, MA 231, ST 311 [ST 380], and a math/ST/CSC elective OR MA 141, MA 241, and MA 242.  The three semester sequence (MA 141,241 and 242) is a prerequisite for PY 205 and 208 and for CH 431 and 433 (CH 431/433 also requires MA 341). This sequence is recommended for those students who plan on graduate studies in Biophysics or a related specialty in Biochemistry, and is required for Biochemistry Honors Option 1. If a student elects to start with MA 141, the sequence of 241 and 242 should be taken. If a student elects to start with MA 131 and MA 231, the sequence of ST 311 [ST 380] and a math/ST/CSC elective should be taken. ST 311 or ST 380 is not a substitute for MA 242.

3

The calculus based physics sequence (PY 205 and 208) is recommended for those students who plan on graduate studies in Biophysics or a related specialty in Biochemistry; and is required for Biochemistry Honors Option 1. If a student chooses PY 205, PY 208 should be taken. 

4

This course is an advised elective in the life sciences.  BIO 240 or BIO 245 is recommended for those students who are interested in applying to the health related professions. This requirement can also be satisfied by an advised elective from upper level life science courses (life science course, 200 level or above; verify with advisor).

5

If a student has chosen the Math sequence of MA 131, MA 231, and ST 311, another course (200 level or above; verify with advisor) in computer science, mathematics or statistics must be chosen.  

6

If BCH 454 is not selected as an option for the Biochemistry Laboratory elective it may be used as an option for the Laboratory Analysis elective.

7

The two semester Physical Chemistry course sequence (CH 431 and 433) is recommended for those students who plan on graduate studies in Biophysics or a related specialty in Biochemistry, and is required for Biochemistry Honors Option 1.  If CH 431 is chosen, CH 433 must be taken. If CH 331 or BCH 330 is chosen, a student must choose an advised elective from upper level courses offered in the sciences, math or computer science (200 level or above; verify with advisor).

8

The corresponding courses for chemistry majors may be substituted (CH 103,104 for CH 101,102; CH 203,204 for CH 201,202; CH 225,226 for CH 221,222; CH 227,228 for CH 223,224).

Career Opportunities

The Biochemistry program provides B.S. graduates with the scientific background and skills required for employment in biochemistry, molecular biology, biotechnology, and genetics and for the health professions of medicine, dentistry, veterinary medicine, pharmacology and related fields. 

Career Titles

  • Agricultural Engineer
  • Agricultural Technician
  • Agronomist
  • Allergists and Immunologists
  • Anesthesiologist (MD)
  • Animal Scientist
  • Biochemist
  • Bioinformatics Scientists
  • Biological Technician
  • Biologist
  • Biology Professor
  • Biophysicist
  • Chemical Engineer
  • Chemical Technicians
  • Chemist
  • Chemistry Professor
  • Conservation Scientist
  • Criminalist
  • Dairy Technologist
  • Environmental Disease Analyst
  • Environmental Research Analyst
  • Environmental Science and Protection Technician
  • Environmental Science Professor
  • Environmental Technician
  • Family Practitioner (MD)
  • Food Science Technicians
  • Food Technologist
  • Forensic Science Technicians
  • General Internists (MD)
  • Geneticist
  • Gynecologist (MD)
  • Hazardous Waste Management Analyst
  • High School Teacher
  • Horticulturist
  • Marine and Aquatic Biologist
  • Microbiologist
  • Middle School Teacher
  • Molecular and Cellular Biologists
  • Pathologist (MD)
  • Perfumer
  • Petroleum Laboratory Assistant
  • Petroleum Technician
  • Pharmacist
  • Pharmacologist
  • Physical Medicine and Rehabilitation Physicians
  • Plant Breeder
  • Radiation Protection Engineer
  • Sales Representative (Chemicals & Drugs)
  • Sales Representative (Medical Equipment)
  • Technical & Scientific Publications Editor
  • Technical Publications Writer
  • Toxicologist
  • Wildlife Biologist

Learn More About Careers

NCcareers.org
Explore North Carolina’s central online resource for students, parents, educators, job seekers and career counselors looking for high quality job and career information.

Occupational Outlook Handbook
Browse the Occupational Outlook Handbook published by the Bureau of Labor Statistics to view state and area employment and wage statistics. You can also identify and compare similar occupations based on your interests.

Career One Stop Videos
View videos that provide career details and information on wages, employment trends, skills needed, and more for any occupation. Sponsored by the U.S. Department of Labor.

Focus 2 Career Assessment (NC State student email address required)
This career, major and education planning system is available to current NC State students to learn about how your values, interests, competencies, and personality fit into the NC State majors and your future career. An NC State email address is required to create an account. Make an appointment with your career counselor to discuss the results.