Toxicology (TOX)

TOX 201  Poisons, People and the Environment  (3 credit hours)  

TOX 201 serves as an introduction to the fascinating world of chemical poisons and covers their numerous and varied effects on human health and the environment. We will learn how and why poisons have played an important history, how to critically evaluate the chemical risk information reported in the media, in addition to the underlying principles of the basic science of poisons.

GEP Natural Sciences

Typically offered in Fall, Spring, and Summer

TOX 401/TOX 501  Principles of Toxicology  (4 credit hours)  

Introduce students to the basic principles of toxicology. Will cover the history and scope of the field; absorption, distribution, metabolism and elimination of toxicants; types and mechanisms of toxic action; carcinogenesis; environmental toxicology as well as human and ecological risk assessment.

Prerequisite: CH 220 or CH 221 or CH 225; BIO 181 or ZO 160

Typically offered in Spring only

TOX 415  Environmental Toxicology and Chemistry  (4 credit hours)  

Environmental toxicology and chemistry including the sources, fate, and effects of chemicals in the environment. Emphasis on contemporary problems in human health and the environment.

Prerequisite: CH 220 or CH 221 or CH 225; BIO 181 or ZO 160 recommended

Typically offered in Fall and Spring

TOX 501/TOX 401  Principles of Toxicology  (4 credit hours)  

Introduce students to the basic principles of toxicology. Will cover the history and scope of the field; absorption, distribution, metabolism and elimination of toxicants; types and mechanisms of toxic action; carcinogenesis; environmental toxicology as well as human and ecological risk assessment.

Prerequisite: CH 220 or CH 221 or CH 225; BIO 181 or ZO 160

Typically offered in Spring only

TOX 515  Environmental Toxicology  (4 credit hours)  

Evaluation of the nature, distribution and significance of microchemical contamination. Emphasis on current, relevant problems.

Prerequisite: Two years of biology

TOX 595  Special Topics  (1-6 credit hours)  
TOX 601  Toxicology Seminar  (1 credit hours)  

Prerequisite: Graduate standing

Typically offered in Fall and Spring

TOX 620  Special Problems  (1-6 credit hours)  

Topics include responsibility in science, environmental fate of chemicals, developmental toxicology, lab rotations, journal club and wildlife toxicology.

Prerequisite: Graduate standing

Typically offered in Fall, Spring, and Summer

TOX 660  Free Radicals In Toxicology  (1 credit hours)  

Introduction to the field of free radicals and their role in toxicology and health; chemical and physical properties of partially reduced oxygen intermediates and the natural biological defense mechanisms.

Prerequisite: BCH 451 and TOX 710

Typically offered in Fall only

TOX 688  Non-Thesis Masters Continuous Registration - Half Time Registration  (1 credit hours)  

For students in non-thesis master's programs who have completed all credit hour requirements for their degree but need to maintain half-time continuous registration to complete incomplete grades, projects, final master's exam, etc.

Prerequisite: Master's student

Typically offered in Spring only

TOX 689  Non-Thesis Master Continuous Registration - Full Time Registration  (3 credit hours)  

For students in non-thesis master's programs who have completed all credit hour requirements for their degree but need to maintain full-time continuous registration to complete incomplete grades, projects, final master's exam, etc. Students may register for this course a maximum of one semester.

Prerequisite: Master's student

Typically offered in Spring only

TOX 690  Master's Exam  (1-9 credit hours)  

For students in non thesis master's programs who have completed all other requirements of the degree except preparing for and taking the final master's exam.

Prerequisite: Master's student

Typically offered in Fall, Spring, and Summer

TOX 693  Master's Supervised Research  (1-9 credit hours)  

Instruction in research and research under the mentorship of a member of the Graduate Faculty.

Prerequisite: Master's student

Typically offered in Fall, Spring, and Summer

TOX 695  Master's Thesis Research  (1-9 credit hours)  

Thesis research.

Prerequisite: Master's student

Typically offered in Fall, Spring, and Summer

TOX 696  Summer Thesis Research  (1 credit hours)  

For graduate students whose programs of work specify no formal course work during a summer session and who will be devoting full time to thesis research.

Prerequisite: Master's student

Typically offered in Summer only

TOX 699  Master's Thesis Preparation  (1-9 credit hours)  

For students who have completed all credit hour requirements and full-time enrollment for the master's degree and are writing and defending their theses.

Prerequisite: Master's student

Typically offered in Fall, Spring, and Summer

TOX 701  Fundamentals of Toxicology  (3 credit hours)  

The basis of toxic action at cellular and molecular levels covering the absorption, distribution, elimination and metabolism of toxicants; toxic action (acute toxicity, carcinogenesis, mutagenesis, organ toxicity, etc.); chemical classes of toxicants; and toxicity testing.

Prerequisite: BCH 451, Senior standing or Graduate standing

Typically offered in Fall only

TOX 704  Chemical Risk Assessment  (1 credit hours)  

Concepts and vocabulary of risk assessment. Risk assessment models and techniques used in cancer and non-cancer risk assessment and strategies for successful risk communications. Case studies of risk assessment and issues of current interest. Utilization of background in toxicology and statistics to examine a critical end-point in toxicological science, the quantitative risk assessment.

Prerequisite: TOX 701, a ST course

TOX 710  Molecular and Biochemical Toxicology  (3 credit hours)  

Fundamental understanding of biochemical, molecular and cellular mechanisms through which xenobiotics alter cellular homeostasis, produce toxicity and alter organ function. Current biochemical, molecular and cellular experimental approaches for study of biochemical mechanisms of toxicity.

Prerequisite: BCH 451; TOX 701

Typically offered in Spring only

TOX 715  Environmental Toxicology  (3 credit hours)  

Evaluation of fundamental processes relating fate and effects of chemicals in the environment. Emphasis on effects of pollutants on non-human species, environmental risk assessment and historically relevant incidents of environmental contaminants.

Prerequisite: Two years of biology

Typically offered in Fall only

TOX 725/CS 725/HS 725/SSC 725  Pesticide Chemistry  (1 credit hours)  

Chemical properties of pesticides including hydration and solvation, ionization, volatilization, lipophilicity, molecular structure and size, and reactivity and classification according to chemical description, mode of action or ionizability. Taughtduring the first 5 weeks of semester. Drop date is last day of 3rd week of the minicourse.

Prerequisite: (CH 201 or CH 203) and (CH 221 or CH 225)

Typically offered in Spring only

TOX 727/CS 727/HS 727/SSC 727  Pesticide Behavior and Fate In the Environment  (2 credit hours)  

Sorption/desorption, soil reactivity, movement, volatilization, bioavailability, degradation and stability of pesticides in the environment. Taught during the last 10 weeks of semester. Drop date is last day of 3rd week of the minicourse.

Prerequisite: CS(HS,SSC,TOX) 725,SSC 200

Typically offered in Spring only

TOX 771/CBS 771  Cancer Biology  (4 credit hours)  

A comprehensive graduate course focusing on the molecular and cellular bases of cancer. Targets of oncogenic mutations will be discussed as well as their impact on cell proliferation, cell survival, and the invasion of normal tissues by tumorigeniccells. State-of-the-art technologies to detect oncogenic mutations and characterize transformed cells will be discussed as well as therapeutic strategies for the rational treatment of cancer.

Prerequisite: CBS 770

Typically offered in Fall only

TOX 795  Special Topics in Toxicology  (1-6 credit hours)  

Typically offered in Fall and Spring

TOX 801  Toxicology Seminar  (1 credit hours)  

Prerequisite: Graduate standing

Typically offered in Fall and Spring

TOX 820  Special Problems In Toxicology  (1-6 credit hours)  

Topics include responsibility in science, environmental fate of chemicals, developmental toxicology, lab rotations, Journal Club, and wildlife toxicology.

Prerequisite: Graduate standing

Typically offered in Fall and Spring

TOX 860  Free Radicals in Toxicology  (1 credit hours)  

Introduction to the field of free radicals and their role in toxicology and health; chemical and physical properties of partially reduced oxygen intermediates and the natural biological defense mechanisms.

Prerequisite: BCH 451 and TOX 710

Typically offered in Fall only

TOX 890  Doctoral Preliminary Examination  (1-9 credit hours)  

For students who are preparing for and taking written and/or oral preliminary exams.

Prerequisite: Doctoral student

Typically offered in Fall, Spring, and Summer

TOX 893  Doctoral Supervised Research  (1-9 credit hours)  

Instruction in research and research under the mentorship of a member of the Graduate Faculty.

Prerequisite: Doctoral student

Typically offered in Fall, Spring, and Summer

TOX 895  Doctoral Dissertation Research  (1-9 credit hours)  

Dissertation research.

Prerequisite: Doctoral student

Typically offered in Fall, Spring, and Summer

TOX 896  Summer Dissertation Research  (1 credit hours)  

For graduate students whose programs of work specify no formal course work during a summer session and who will be devoting full time to thesis research.

Prerequisite: Doctoral student

Typically offered in Summer only

TOX 899  Doctoral Dissertation Preparation  (1-9 credit hours)  

For students who have completed all credit hour, full-time enrollment, preliminary examination, and residency requirements for the doctoral degree, and are writing and defending their dissertations.

Prerequisite: Doctoral student

Typically offered in Fall, Spring, and Summer