Biomedical Engineering (BME)

BME 201  Computer Methods in Biomedical Engineering  (3 credit hours)  

Students develop computer-based problem solving techniques using Excel and MATLAB to solve introductory problems in Biomedical Engineering. Emphasis is on developing solution algorithms, implementing these with spreadsheets and computer programming, and presenting results in a clear and concise manner. Students registered for BME 201 who fail to matriculate into BME will be dropped from the course.

Prerequisite: BME matriculated students

Typically offered in Fall only

BME 203/MSE 203  Introduction to the Materials Science of Biomaterials  (3 credit hours)  

This course introduces fundamental physical principles governing the structure, processing, properties and performance of metallic, ceramic and polymeric materials. Relationships are developed defining how mechanical, physical and chemical properties are controlled by microstructure and chemistry. Material failure modes are develped with an emphasis on biocompatibility and the applications/performance of materials in the human body. Basic aspects of material biocompatibility are presented, leading into studies of the current and future applications of biomaterials.

Prerequisite: C- or better in CH 101, CH 102 and PY 205

Typically offered in Fall and Spring

BME 204  Biomedical Measurements  (3 credit hours)  

This course will introduce students to modern topics in biomedical engineering and areas of emphasis in the biomedical engineering curriculum through the study and use of biomedical measurement tools. The course will include a lecture and a laboratory c

Prerequisite: BME Majors

Typically offered in Fall and Spring

BME 205  Introduction to Biomedical Mechanics  (4 credit hours)  

Study of the state of rest or motion of bodies subjected to the action of forces. Properties of force systems, free body diagrams, concepts of equilibrium, kinematics of particles, newton's laws, conservational principles of energy of momentum in mechanics, mechanical vibrations and their applications in biomedical systems. Restricted to student in the Biomedical Engineering Department.

Credit cannot be received for both BME 205 and (CE 214 or MAE 206)

Typically offered in Spring only

BME 207  Biomedical Electronics  (4 credit hours)  

Fundamentals of analog and digital circuit analysis and design as applied to biomedical instrumentation and measurement of biological potentials. Passive circuit components, node and mesh analysis, transient behavior, operational amplifiers, frequency response, analog filter design, diode, transistors, biological signal acquisition, binary math and logical operators, digital circuit design, circuit simulation tools and techniques. Laboratory exercises supplement the topics presented in class lectures.

Prerequisites: PY 208/209, BME Majors Only

Typically offered in Spring only

BME 209  Introduction to the Materials Science of Biomaterials  (4 credit hours)  

This course covers the chemistry, physics, and engineering theory underlying materials science and also discusses the diagnostic and analytical techniques necessary to assess these properties experimentally. This strong foundation prepares students to conceive and build better materials for a wide assortment of biomedical applications.

Co-req: PY 208/209. Pre-req: BME Students Only. Credit cannot be received for BME 209 and (MSE 200, MSE 201, MSE 203 or BME 203)

Typically offered in Fall only

BME 215  Biomedical Mechanics Laboratory  (1 credit hours)  

This laboratory is part of BME 205 - Biomedical Mechanics and complements it with relevant labs and examples. Statics and dynamics subjects will be studied with experimental techniques, including strain gauges and accelerometers, and computational methods, including finite-element analysis and motion capture. Finally, the human arm will be studied to derive forces, moments, and kinematic properties during various exercises. BME student only.

Co-requisites: MAE 208

Typically offered in Spring only

BME 217  Biomedical Electronics Laboratory  (1 credit hours)  

Laboratory in analog and digital circuit analysis. Electrical safety; Exercises in resistor networks, capacitors and inductors, steady-state and dynamic circuit behavior, active circuits, amplifiers, logic gates, combinatorial and sequential circuits, elementary digital system design, A/D conversion, biomedical applications.

Prerequisite: ECE 331, BME Majors

Typically offered in Spring only

BME 219  Materials Science of Biomaterials Lab  (1 credit hours)  

Introductory laboratory experience focused on integrating biological engineering and materials engineering principles by exploring key topics in materials science. Topics include biomaterial fabrication, evaluation of their physical properties and interpretation of results.

Pre-requisite: MSE 200 or MSE 201 or MSE/BME 203. Credit cannot be received for both BME 219 and BME 209

Typically offered in Fall only

BME 295  Research in Biomedical Engineering for Undergraduates  (1-3 credit hours)  

Opportunity for faculty mentored research in biomedical engineering. Approved plan of work required with significant independent research culminating in a final paper. Students must identify an advisor or co-advisor from within the BME faculty with whom

R: BME Majors, Departmental Approval Required

Typically offered in Fall and Spring

BME 298  Biomedical Engineering Design and Manufacturing I  (2 credit hours)  

This is the first in a series of four courses in Biomedical Design. The course introduces the tools and problem-solving skills required in the field of Biomedical Engineering.

Co-requisites: PY 208/209, BME Majors only

Typically offered in Fall only

BME 299  BME Design and Manufacturing I Lab  (1 credit hours)  

BME 299 together with BME 252 or another course in CAD design fulfills the requirements of BME 298 Biomedical Engineering Design and Manufacturing I. In this course students learn some of the practical fundamentals of electronics manufacturing. Activities include use of bench equipment, soldering techniques, circuit board types, how to identify common electronic components and how they work in a circuit and simple C programming for microcontrollers.

Prerequisite: BME 252. Credit cannot be received for both BME 298 and BME 299

Typically offered in Fall only

BME 301  Human Physiology : Electrical Analysis  (4 credit hours)  

This course includes a quantitative approach to human physiology from the biomedical engineering perspective with an emphasis on neural, sensory, muscle, and cardiac physiology. Autonomic and somatic motor control will be discussed. Engineering applications, including neural stimulators, functional imaging, cochlear implants, artificial noses, vestibular implants, visual implants, artificial larynges, pacemakers and defibrillators will be discussed. Assignments include computer-based exercises using MATLAB.

Prerequisites: BIO 183, BM(M)E 201, [BME 210 or BM(M)E 207]

Typically offered in Fall only

BME 302  Human Physiology: Mechanical Analysis  (4 credit hours)  

This course explores a quantitative approach to human physiology from the biomedical engineering perspective with an emphasis on systems physiology described using mechanical properties. Topics include the physiological and mechanical behavior of the blood vessels, lungs, kidney muscles and larynx. In the course lab exercises, students investigate mechanical properties of fluids, electrolyte exchange in dialysis, spirometry and blood pressure measurement among other topics. The course culminates with the design of a novel laboratory experiment.

Prerequisite: BIO 183, [BM(M)E 205 or MAE 208], [BM(M)E 209 or BMME 150]

Typically offered in Spring only

BME 315  Biotransport  (3 credit hours)  

Quantification and modeling of heat and mass transfer in biomedical systems. Topics include heat transfer rate equations, conservation of energy, steady-state and transient heat transfer, Brownian motion, Fick's laws, conservation of mass equations, molecular transport through membranes, porous media, Stoke-Einstein relations, boundary layer theory, mass transfer coefficients and hemodialysis.

Prerequisite: BIO 183 and BME/BMME 201 and BME/BMME 205 or MAE 208 and MA 341 or MA 331

Typically offered in Spring only

BME 325  Biochemistry for Biomedical Engineers  (3 credit hours)  

An overview of how alterations in bioenergetics, enzyme catalysis, protein and membrane structure, carbohydrate, lipid and nucleic acid metabolism affect human health and how biomedical engineering tools are used to detect and monitor the problems by understanding these biochemical processes. Topics include: Biological Thermodynamics, Energy of macromolecular structure and binding, Structure/function of proteins, enzymes and nucleic acids, Kinetics, enzyme catalysis and biochemical network analysis, Generation of chemical and electrical potential in membranes, Carbohydrate/lipid/protein metabolism and energy production, DNA synthesis, transcription, Technologies used to monitor/detect biochemical processes including clinical imaging modalities.

Prerequisite: CH 221, (BME 209 or BME 203)

Typically offered in Fall only

BME 335  Biomaterials  (3 credit hours)  

Fundamental sciences behind the design and selection of biomaterials, including crystallography, polymer science, characterization, mechanical testing, and surface preparation. Integration of biomaterials into the body and its response, including inflammation and rejection. Semester-long research project.

Pre-req: BIO 183, (BME 209 or BME 203)

Typically offered in Spring only

BME 342  Analytical and Experimental Methods for Biomedical Engineers  (3 credit hours)  

Experimental and analytic tools are developed and used to solve problems in biomedical engineering. Techniques include kinematic analysis, closed form and finite element analysis of stresses and strains in a body, and failure analysis. Transducersnecessary for experimental analysis and testing are introduced. Students learn advanced software packages such as the finite element program ANSYS and the dynamic analysis program ADAMS to assist in their analyses.

Prerequisite: BME 201; MAE 208 or CE 215; MAE 214 or CE 313; MA 341

Typically offered in Spring only

BME 345  Biomedical Solid Mechanics  (3 credit hours)  

This course covers topics ranging from multi-body systems to stress superposition to failure criteria to prepare students for the more advanced subjects of biomechanics and rehabilitation engineering. Topics include the following: Free-body diagrams, Multibody statics and dynamics, Linkage kinematics and kinetics, Anthropometric kinematics, Stress/strain/torsion, Beam bending, Stress superposition, Constitutive relationship, Strain gauges, Finite-element analysis, Failure analysis, Failure mechanisms.

Typically offered in Spring only

BME 355  Biocontrols  (3 credit hours)  

Quantitative analysis of dynamic and feedback control systems, including modeling of physiological systems and physiological control systems, system time and frequency responses, control characteristics, and stability analysis. Design techniques for feedback systems in biomedical applications.

Prerequisite: MA 341; Corequisite: BME 311

Typically offered in Spring only

BME 365  Linear Systems in Biomedical Engineering  (3 credit hours)  

Fundamentals of linear systems analysis as applied to problems in biomedical modeling and instrumentation. Properties of biomedical systems and signals. Representation of continuous- and discrete-time signals and system response. Convolution. Fourie

Pre-reqs: [BM(M)E 207 or BME 210], BM(M)E 201. Co-reqs: MA 341 or MA 331

Typically offered in Fall only

BME 375  Biomedical Microcontroller Applications  (3 credit hours)  

Overview of microcontroller-based systems, including applications, architecture, number systems, and languages. Students gain experience using a PIC-based microcontroller to input information from a user and output information using LEDs and LCD displays. Student will learn capabilities of the PIC through in class exercises and weekly programming assignments. Both assembly language and PIC-based C are used. Students develop a PIC-based heart rate monitor and work in pairs on a BME-related project of their choice.

Pre-reqs: [BM(M)E 207 or BME 210], BM(M)E 201. Co-reqs: BM(M)E 385 or BME 422

Typically offered in Fall only

BME 385  Bioinstrumentation  (3 credit hours)  

Fundamentals of biomedical instrument design and implementation. Sensing mechanisms, sensor microfabrication methods, sensor interfacing circuits, analog-to-digital conversion, biosignal capture and storage, embedded microprocessors, data compression methods, system integration and prototyping. Laboratory exercises using LabVIEW and MATLAB, supplement the topics presented in class lectures. Students build a sensor using cleanroom facilities in the BME department as part of a semester-long design project.

Pre-reqs: [BM(M)E 207 or BME 219], BM(M)E 201

Typically offered in Fall only

BME 398  Biomedical Engineering Design and Manufacturing II  (2 credit hours)  

Students will be required to continue their use of the tools learned in Biomedical Design and Manufacturing I in the context of modern design practices and manufacturing processes. The organizational and project management tools of moderm design will be introduced, and a technical discussion of a modern manufacturing technology will be introduced each week.

Pre-reqs: BM(M)E 298, [BM(M)E 207 or BME 210], BM(M)E 201

Typically offered in Spring only

BME 412  Biomedical Signal Processing  (3 credit hours)  

Fundamentals of continuous- and discrete-time signal processing as applied to problems in biomedical instrumentation. Properties of biomedical signals and instruments. Descriptions of random noise and signal processes. Interactions between randombiom

Pre-reqs: BM(M)E 365 or BME 311

Typically offered in Spring only

BME 418/BME 518/ECE 518/ECE 418  Wearable Biosensors and Microsystems  (3 credit hours)  

This course surveys the methods and application of wearable electronics and microsystems to monitor human biometrics, physiology, and environmental conditions. Topics covered include wearable electrocardiograms, blood-glucose monitors, electronic tattoos, wearable energy harvesting, "smart" clothing, body area networks, and distributed population networks. Critical comparison of different sensor modalities, quantitative metrics, and how their limitations in realistic applications define the selection, design, and operation criteria of one type of sensor over another will be considered.

Prerequisite: Senior standing

Typically offered in Fall only

BME 425/BME 525  Bioelectricity  (3 credit hours)  

Quantitative analysis of excitable membranes and their signals, including plasma membrane characteristics, origin of electrical membrane potentials, action potentials, voltage clamp experiments, the Hodgkin-Huxley equations, propagation, subthresholdstimuli, extracellular fields, membrane biophysics, and electrophysiology of the heart. Design and development of an electrocardiogram analysis system.

Prerequisite: BME 302 or (ZO 421 and a course in electrical circuits)

Typically offered in Spring only

BME 444/BME 544  Orthopaedic Biomechanics  (3 credit hours)  

Students study human body kinematics, force analysis of joints, and the structure and composition of biological materials. Emphasis is placed on the measurement of mechanical properties and the development and understanding of models of biological material mechanical behavior.

P: BM(M)E 301, BM(M)E 302, [BM(M)E 345 or MAE 214 or CE 313]

Typically offered in Fall only

BME 451  Biomedical Engineering Senior Design I  (3 credit hours)  

This course encompasses the project proposal and design concepts, including: individual pre-proposals, team proposals, project planning, scheduling, needs assessment, product requirements, competitive landscape and patent review, business risks, design concepts, and phase reviews. BME majors only.

Prerequisites: BME 302, BME 352, and completion of two of the suggested BME electives for their area of emphasis ; BME majors; Corequisites: ENG 331 or ENG 333

Typically offered in Fall only

BME 452  Biomedical Engineering Senior Design II  (3 credit hours)  

This course is a continuation of BME 451 moving from proposal and concepts into manufacturing, prototyping, and testing. The deliverables in this course include: detailed manufacturing specifications, biomaterials review, supplier identification, product feasibility, issues tracking, manufacturing planning, bill of materials, product risks, qualification protocol, IP disclosure, process validation planning, regulatory review, design history file audit, lessons learned, and phase reviews.

Prerequisite: BME 451, BME Majors

Typically offered in Spring only

BME 462  Biomaterials Characterization  (3 credit hours)  

Introductory laboratory experience focused on integrating engineering and biological principles by exploring key topics in biomaterials. Topics include evaluation and interpretation of experimental results, modeling and testing of tissues and cells, and biomaterial/tissue, cell interactions. BME and MSE Majors only; Juniors and Seniors.

Pre-reqs: [BM(M)E 325 or BCH351 or BCH 451], [BM(M)E 335 or MSE 485] and BME Majors.

Typically offered in Spring only

BME 466/TE 566/BME 566/TE 466  Polymeric Biomaterials Engineering  (3 credit hours)  

In-depth study of the engineering design of biomedical polymers and implants. Polymeric biomaterials, including polymer synthesis and structure, polymer properties as related to designing orthopedic and vascular grafts. Designing textile products as biomaterials including surface modification and characterization techniques. Bioresorbable polymers.

Prerequisite: PY 208 and (TE 200 or CH 220 or CH 221 or CH 225) and (MAE 206 or CE 214)

Typically offered in Fall only

BME 467/TE 467  Mechanics of Tissues & Implants Requirements  (3 credit hours)  

Application of engineering and biological principles to understand the structure and performance of tendons, ligaments, skin, and bone; bone mechanics; viscoelasticity of soft biological tissues; models of soft biological tissues; mechanics of skeletal muscle; and tissue-derived devices as well as interfaces between native tissues and synthetic devices.

Prerequisite: (ZO 160 or BIO 183) and (MAE 214 or CE 225)

Typically offered in Spring only

BME 481  Quality Management Systems for Engineers  (3 credit hours)  

This course is designed for biomedical engineering students who plan to work in industry. The course covers industry related topics including team work, conflict resolution, manufacturing and specifications, gap analysis, and root cause of analysis. Design topics including design of experiments, and standards and regulations relevant to the biomedical engineering profession are also covered. Lean and six sigma are taught with an option to test for a six sigma green belt if a six sigma project is completed in the following semester.

Co-reqs: BMME 697 or BME 451

Typically offered in Fall only

BME 483/BEC 483/BME 583/BEC 583  Tissue Engineering Technologies  (2 credit hours)  

In this half-semester laboratory module, students will gain practical experience with two key elements of tissue engineering: tissue building and angiogenesis. Using advanced culture techniques, students will construct a complex living tissue that closely resembles its natural counterpart, then assess its ability to support ingrowth of capillaries (angiogenesis). The effects of different biomaterials and angiogenic factors will be evaluated. The engineered tissue will be embedded, sectioned and stained for histological analysis.

Prerequisite: BIT 466/566 or permission of instructor

Typically offered in Fall only

BME 484/BME 584  Fundamentals of Tissue Engineering  (3 credit hours)  

This course covers essential concepts of organ and tissue design and engineering using living components, including cell-based systems and cells/tissues in combination with biomaterials, synthetic materials and/or devices. Topics include: In vivo tissue structure and function; Isolation and culture of primary cells and stem cells; Principles of cellular differentiation; Mass transport processes in cell culture systems; Design, production and seeding of scaffolds for 3D culture; Design of bioreactors to support high-density cell growth; State-of-the-art engineered tissue systems; Clinical translation; and Ethics.

Prerequisite: BIO 183, CH 221, and (MAE 201 or MSE 301 or CHE 315 or TE 303 or BME 315 or BME 325)

Typically offered in Spring only

BME 490  Special Topics in Biomedical Engineering  (1-4 credit hours)  

Offered as needed for presenting material not normally available in regular BME Department courses or for new BME courses on a trial basis.

Typically offered in Fall, Spring, and Summer

BME 498  Undergraduate Research in Biomedical Engineering  (3 credit hours)  

Opportunity for hands-on faculty mentored research project in biomedical engineering. Course may be a stand-alone project completed in one semester/summer or serve as part of a two-semester project. Approved plan of work required with significant indepe

Typically offered in Fall and Spring

BME 501  Biomedical Innovation and Entrepreneurship I - Needs Discovery  (4 credit hours)  

This course utilizes clinical immersion to identify medical device and other healthcare opportunities. Students will be exposed to diverse healthcare environments and learn to triage opportunities based on financial, regulatory and intellectual property landscapes. Guest lectures will feature experts in the medical device, pharmaceutical and healthcare industries as well as local entrepreneurs.

Prerequisite: Graduate Standing; R: Restricted to students enrolled in the M.S. Biomedical Engineering Program

Typically offered in Summer only

BME 502  Biomedical Innovation and Entrepreneurship II - Design and Regulation  (4 credit hours)  

This course teaches path-to-market concepts including regulatory aspects unique to medical devices and pharmaceuticals. Topics include detailed analyses of Phase I-IV clinical trials, 510(k) and PMA approvals, Investigational Device Exemption (IDE) Investigational New Drug (IND) application, Good Laboratory Practices (GLP) and clinical research organizations (CROs). Students will participate in frequent visits to local biotech companies. Guest lectures will feature experts in FDA processes, clinical research and early stage biotech ventures.

Prerequisite: Graduate Standing; R: Restricted to students enrolled in the M.S. Biomedical Engineering Program

Typically offered in Fall only

BME 503  Biomedical Innovation and Entrepreneurship III - Product Development  (4 credit hours)  

This course covers product development and project management for new biomedical-related products from accessing various streams of funding to allocation of resources for rapid prototyping and scale-up manufacturing. Students will visit local biotech co

Prerequisite: Graduate Standing; R: Restricted to students enrolled in the M.S. Biomedical Engineering Program

Typically offered in Spring only

BME 518/ECE 518/ECE 418/BME 418  Wearable Biosensors and Microsystems  (3 credit hours)  

This course surveys the methods and application of wearable electronics and microsystems to monitor human biometrics, physiology, and environmental conditions. Topics covered include wearable electrocardiograms, blood-glucose monitors, electronic tattoos, wearable energy harvesting, "smart" clothing, body area networks, and distributed population networks. Critical comparison of different sensor modalities, quantitative metrics, and how their limitations in realistic applications define the selection, design, and operation criteria of one type of sensor over another will be considered.

Prerequisite: Senior standing

Typically offered in Fall only

BME 522/ECE 522  Medical Instrumentation  (3 credit hours)  

Fundamentals of medical instrumentation systems, sensors, and biomedical signal processing. Example instruments for cardiovascular and respiratory assessment. Clinical laboratory measurements, theraputic and prosthetic devices, and electrical safetyrequirements. Students should have background in electronics design using operational amplifiers.

Typically offered in Spring only

BME 525/BME 425  Bioelectricity  (3 credit hours)  

Quantitative analysis of excitable membranes and their signals, including plasma membrane characteristics, origin of electrical membrane potentials, action potentials, voltage clamp experiments, the Hodgkin-Huxley equations, propagation, subthresholdstimuli, extracellular fields, membrane biophysics, and electrophysiology of the heart. Design and development of an electrocardiogram analysis system.

Prerequisite: BME 302 or (ZO 421 and a course in electrical circuits)

Typically offered in Spring only

BME 540  Nanobiotechnology Processing, Characterization, and Applications  (3 credit hours)  

Topics at the interface of nanoscale science and biotechnology will be discussed. Chemical, physical, and biological properties of nanostructured biomaterials, devices, and systems. Lectures and problem-based learning will be used to present development of nanobiotechnology-enhanced materials and devices.

Prerequisite: BIO 183 and PY 212

Typically offered in Spring only

BME 543  Cardiovascular Biomechanics  (3 credit hours)  

Engineering principles are applied to the cardiovascular system. Anatomy of cardiovascular system; form and function of blood and blood vessels. Electric analogs; continuum mechanics with derivation of equations of motion; and constitutive models of soft tissue mechanics, with attention to normal, diseased, and adaptive processes. Programming project required.

BME 544/BME 444  Orthopaedic Biomechanics  (3 credit hours)  

Students study human body kinematics, force analysis of joints, and the structure and composition of biological materials. Emphasis is placed on the measurement of mechanical properties and the development and understanding of models of biological material mechanical behavior.

P: BM(M)E 301, BM(M)E 302, [BM(M)E 345 or MAE 214 or CE 313]

Typically offered in Fall only

BME 550  Medical Imaging: Ultrasonic, Optical, and Magnetic Resonance Systems  (3 credit hours)  

Physical and mathematical foundations of ultrasonic, optical, and magnetic resonance imaging systems in application to medical diagnostics. Each imaging modality is examined on a case-by-case basis, highlighting the following critical system characteristics: (1) underlying physics of the imaging system, including the physical mechanisms of data generation and acquisition; (2) image creation, and (3) basic processing methods of high relevance, such as noise reduction.

Prerequisite: BME 412, ST 370 or ST 371, and PY 208

Typically offered in Fall only

BME 551  Medical Device Design  (3 credit hours)  

Student multidisciplinary teams work with local medical professionals to define specific medical device concepts for implementation. Medical specialty immersion with clinical departments at local medical centers; design input based on stakeholder-needs

Typically offered in Fall only

BME 552  Medical Device Design II  (3 credit hours)  

Student groups build and test prototypes of devices designed in the first course of this series. Good manufacturing practices; process validation; FDA quality system regulations; design verification and validation; regulatory approval planning; andinte

BME 560  Medical Imaging: X-ray, CT, and Nuclear Medicine Systems  (3 credit hours)  

Overview of medical imaging systems using ionizing radiation. Interaction of radiation with matter. Radiation production and detection. Radiography systems and applications. Tomography. PET and SPECT systems and applications.

Prerequisite: BME 311, ST 370 or ST 371, and PY 208

BME 566/TE 466/BME 466/TE 566  Polymeric Biomaterials Engineering  (3 credit hours)  

In-depth study of the engineering design of biomedical polymers and implants. Polymeric biomaterials, including polymer synthesis and structure, polymer properties as related to designing orthopedic and vascular grafts. Designing textile products as biomaterials including surface modification and characterization techniques. Bioresorbable polymers.

Prerequisite: PY 208 and (TE 200 or CH 220 or CH 221 or CH 225) and (MAE 206 or CE 214)

Typically offered in Fall only

BME 583/BEC 583/BME 483/BEC 483  Tissue Engineering Technologies  (2 credit hours)  

In this half-semester laboratory module, students will gain practical experience with two key elements of tissue engineering: tissue building and angiogenesis. Using advanced culture techniques, students will construct a complex living tissue that closely resembles its natural counterpart, then assess its ability to support ingrowth of capillaries (angiogenesis). The effects of different biomaterials and angiogenic factors will be evaluated. The engineered tissue will be embedded, sectioned and stained for histological analysis.

Prerequisite: BIT 466/566 or permission of instructor

Typically offered in Fall only

BME 584/BME 484  Fundamentals of Tissue Engineering  (3 credit hours)  

This course covers essential concepts of organ and tissue design and engineering using living components, including cell-based systems and cells/tissues in combination with biomaterials, synthetic materials and/or devices. Topics include: In vivo tissue structure and function; Isolation and culture of primary cells and stem cells; Principles of cellular differentiation; Mass transport processes in cell culture systems; Design, production and seeding of scaffolds for 3D culture; Design of bioreactors to support high-density cell growth; State-of-the-art engineered tissue systems; Clinical translation; and Ethics.

Prerequisite: BIO 183, CH 221, and (MAE 201 or MSE 301 or CHE 315 or TE 303 or BME 315 or BME 325)

Typically offered in Spring only

BME 590  Special Topics in Biomedical Engineering  (1-6 credit hours)  

A study of topics in the special fields under the direction of the graduate faculty.

Prerequisite: Senior or Graduate standing in Engineering or physical or biological sciences or textiles

Typically offered in Fall, Spring, and Summer

BME 620  Special Problems in Biomedical Engineering  (1-6 credit hours)  

Selection of a subject by each student on which to do research and write a technical report on the results. Subject may pertain to the student's particular interest in any area of study in biomedical engineering.

Prerequisite: Graduate standing in BME

Typically offered in Fall, Spring, and Summer

BME 650  Internship in Biomedical Engineering  (1 credit hours)  

Students obtain professional experience through advanced engineering work in industrial and commercial settings under joint supervision of a member of the graduate faculty and an outside professional.

Prerequisite: Graduate standing in BME

Typically offered in Summer only

BME 685  Master's Supervised Teaching  (1-3 credit hours)  

Teaching experience under the mentorship of faculty who assist the student in planning for the teaching assignment, observe and provide feedback to the student during the teaching assignment, and evaluate the student upon completion of the assignment.

Prerequisite: Master's student

Typically offered in Fall, Spring, and Summer

BME 693  Master's Supervised Research  (1-9 credit hours)  

Instruction in research and research under the mentorship of a member of the Graduate Faculty.

Prerequisite: Master's student

Typically offered in Fall and Spring

BME 695  Master's Thesis Research  (1-9 credit hours)  

Thesis research.

Prerequisite: Master's student

Typically offered in Fall, Spring, and Summer

BME 696  Summer Thesis Research  (1 credit hours)  

For graduate students whose programs of work specify no formal course work during a summer session and who will be devoting full time to thesis research.

Prerequisite: Master's student

Typically offered in Summer only

BME 699  Master's Thesis Preparation  (1-9 credit hours)  

For students who have completed all credit hour requirements and full-time enrollment for the master's degree and are writing and defending their thesis.

Prerequisite: Master's student

Typically offered in Fall, Spring, and Summer

BME 790  Advanced Special Topics in Biomedical Engineering  (1-6 credit hours)  

A study of topics in advanced or emerging special areas under the direction of the graduate faculty. Experimental doctoral level courses.

Prerequisite: Graduate standing in engineering, physical, or biological sciences or textiles

Typically offered in Fall, Spring, and Summer

BME 802  Advanced Seminar in Biomedical Engineering  (1 credit hours)  

Elaboration of advanced subject areas, techniques and methods related to professional interest through presentations of personal and published works; opportunity for students to present and critically defend ideas, concepts, and inferences; opportunity for distinguished scholars to present results of their work. Discussions to uncover analytical solutions and analogies between problems in biomedical engineering and other technologies, and to present relationship of biomedical engineering to society.

Prerequisite: Doctoral student in BME or other engineering, physical science, or biological science majors, or textiles

Typically offered in Fall and Spring

BME 885  Doctoral Supervised Teaching  (1-3 credit hours)  

Teaching experience under the mentorship of faculty who assist the student in planning but the teaching assignment, observe and provide feedback to the student during the teaching assignment, and evaluate the student upon completion of the assignment.

Prerequisite: Doctoral student

Typically offered in Fall, Spring, and Summer

BME 890  Doctoral Preliminary Examination  (1-9 credit hours)  

For students who are preparing for and taking written and/or oral preliminary exams.

Prerequisite: Doctoral student

Typically offered in Summer only

BME 893  Doctoral Supervised Research  (1-9 credit hours)  

Instruction in research and research under the mentorship of a member of the Graduate Faculty.

Prerequisite: Doctoral student

Typically offered in Fall and Spring

BME 895  Doctoral Dissertation Research  (1-9 credit hours)  

Dissertation research.

Prerequisite: Doctoral student

Typically offered in Fall, Spring, and Summer

BME 896  Summer Dissertation Research  (1 credit hours)  

For graduate students whose programs of work specify no formal course work during a summer session and who will be devoting full time to thesis research.

Prerequisite: Doctoral student

Typically offered in Summer only

BME 899  Doctoral Dissertation Preparation  (1-9 credit hours)  

For students who have completed all credit hour, full-time enrollment, preliminary examination, and residency requirements for the doctoral degree, and are writing and defending their dissertations.

Prerequisite: Doctoral student

Typically offered in Fall, Spring, and Summer