Comparative Biological Science (CBS)

CBS 493  Undergraduate Research in Biomedical Sciences  (1-3 credit hours)  

A learning experience in College of Veterinary Medicine within an academic framework that utilizes campus facilities and resources for supervised undergraduate research. Arrangements must be initiated by the student and be approved by a faculty adviser, the college Undergraduate Research Coordinator, and the Associate Dean of Research Training and Graduate Programs. Students who enroll in this course are required in this course to complete and submit an Agreement for Non-Standard Courses form through Registration and Records.

Requisite: Sophomore Standing or Above

Typically offered in Fall and Spring

CBS 510  Animal Production Topics  (1-3 credit hours)  

Students will be provided with experience in management of production animals with an emphasis on the veterinary aspects of population health. Experience will come in the form of hands-on experiences and working through relevant literature to specific a

Typically offered in Fall and Spring

CBS 550  Population Medicine Forum  (1 credit hours)  

Population medicine forum is a seminar-based class during which current topics in population health are presented and discussed. Topics covered include: Outbreak investigation, observational epidemiologic research, risk analysis, spatial analysis, the application of unique diagnostic technologies and epidemiologic modeling.

Typically offered in Fall and Spring

CBS 565  Fundamentals of Biomedical Sciences  (3 credit hours)  

Introductory course for students interested in gaining a broad understanding of: comparative genomics, comparative immunology, comparative physiology, pharmacokinetics, emerging zoonotic diseases, epidemiology and translational research models and methods. This course also provides an overview of current technologies relevant to comparative biomedical research and a foundation for implementing the scientific method (e.g. experimental design, data analyses, statistics). Priority will be given tofirst-year students in CBS graduate program; Enrollment of all students requires consent of instructor.

Typically offered in Fall only

CBS 570  Methods in Biomedical Sciences  (1 credit hours)  

Introductory course for students interested in gaining a broad understanding of various laboratory methods used in molecular, cellular and "omics" based biomedical research.

Typically offered in Fall only

CBS 579  Advanced Specialty Training  (1-3 credit hours)  

This course is designed to give students clinical experience and training to understand basic health management strategies, handle clinical evaluations, use diagnostic tools to facilitate accurate diagnosis, and develop prevention and/or treatment plans for health management. This course is restricted to Students in the SVM program.

Typically offered in Fall and Spring

CBS 580  Clinical Veterinary Epidemiology  (3 credit hours)  

To expose students to the concepts and principles of epidemiology from the perspective of assessing health and disease in animal and human populations, and the measures to control disease status. Specifically to study the principles and concepts ofveterinary epidemiology, to learn basic epidemiology methodology, critically review major veterinary care studies, and enhance oral and written communication skills.

Prerequisite: ST 511

Typically offered in Fall only

CBS 586  One Health: From Philosophy to Practice  (2 credit hours)  

Graduate/professional seminar (with team project) addressing intersections of veterinary medicine, human medicine, and environmental health. Co-listed at UNC CH Gillings School of Global Public Health and Duke University School of Medicine. Includes participants from these three institutions, plus related private-sector members, non-governmental organizations, and government professionals. Its purpose is to facilitate understanding of one health as a system of systems, and promote cross-campus and cross-discipline interactions. Weekly evening course held at NC Biotechnology Center, RTP. Requires graduate student standing at NCSU or professional student standing within the College of Veterinary Medicine. Limit: 15 students per university.

Typically offered in Fall only

CBS 595  Special Topics  (1-6 credit hours)  
CBS 611  Principles of Collaboration and Team Science  (2 credit hours)  

The focus of this course is exploring how to effectively communicate as a member of a cross-disciplinary team. Specifically, this course offers strategies and techniques about engaging in team science to pursue complex research questions, work effectively with team members, identify and address unconscious bias, and assess team performance in order to produce high impact research outcomes. To that end, we will examine aspects of group process and communication related to professional relationship development, teamwork, leadership, and conflict resolution.

Typically offered in Spring only

CBS 615  Advanced Animal Production Topics  (1-3 credit hours)  

Students will be provided with practice and experience in advanced topics related to management of production animals with an emphasis on the veterinary aspects of population health. Actual in-the-field, hands-on practice and investigation of relevant literature will provide the basis for study of advanced animal production topics. Course is restricted to students in the SVM program

Prerequisite: SVM 510

Typically offered in Fall and Spring

CBS 624  Special Problems In Gastrointestinal Physiology  (1 credit hours)  

1 credit for a 1-hour in depth discussion session of current journal articles presented by students on the subject of gastrointestinal physiology. Journals recommended include the American Journal of Physiology, Gut and Gastroenterology. Each session will focus on one student's selected paper. MS students are expected to present 1 paper, and PhD students are expected to present up to 2 papers each semester. Students should be enrolled in a graduate course of study in a field related to or focused on physiology. Undergraduate students require special permission.

Typically offered in Fall and Spring

CBS 635  MR Advanced Reading  (1-3 credit hours)  

Typically offered in Fall and Spring

CBS 649  Issues in Preventive Medicine and Public Health  (1 credit hours)  

Issues in Preventive Medicine and Public Health is a literature review course designed to assist students with their preparation for careers in public health, ecosystem health, biosecurity and public policy, disaster management, and application for Board Certification in the American College of Preventive Veterinary Medicine. Permission by course instructor required for enrollment.

Prerequisite: A prior degree in veterinary medicine or public health

CBS 650  Population Medicine Forum  (1 credit hours)  

Population medicine forum is a seminar-based class during which current topics in population health are presented and discussed. Topics covered include: Outbreak investigation, observational epidemiologic research, risk analysis, spatial analysis, the application of unique diagnostic technologies and epidemiologic modeling.

Typically offered in Fall and Spring

CBS 662  Professional Conduct in Biomedical Research  (1 credit hours)  

Plagiarism, authorship, fraud, safety, sexual harassment, IACUC, consulting agreements, serving as an expert witness, contacting elected officials, working with press, human subjects committee, and related topics.

Typically offered in Spring only

CBS 680  MR Special Topics  (1-6 credit hours)  

Typically offered in Fall and Spring

CBS 681  MR Seminar  (1-3 credit hours)  

Typically offered in Fall and Spring

CBS 682  Seminar - Poultry Medicine  (1-3 credit hours)  

Typically offered in Fall, Spring, and Summer

CBS 683  MR Other Special Topics  (1-6 credit hours)  

Typically offered in Fall and Spring

CBS 684  Internship  (1-3 credit hours)  

Credit for internships in fields related to the comparative biomedical sciences.

Typically offered in Fall, Spring, and Summer

CBS 685  Master's Supervised Teaching  (1-3 credit hours)  

Teaching experience under the mentorship of faculty who assist the student in planning for the teaching assignment, observe and provide feedback to the student during the teaching assignment, and evaluate the student upon completion of the assignment.

Prerequisite: Master's student

Typically offered in Fall, Spring, and Summer

CBS 686  Food Animal Health Teachings  (1-3 credit hours)  
CBS 693  Master's Supervised Research  (1-9 credit hours)  

Instruction in research and research under the mentorship of a member of the Graduate Faculty.

Prerequisite: Master's student

Typically offered in Fall, Spring, and Summer

CBS 695  Master's Thesis Research  (1-9 credit hours)  

Thesis research

Prerequisite: Master's student

Typically offered in Fall, Spring, and Summer

CBS 696  Summer Thesis Research  (1 credit hours)  

For graduate students whose programs of work specify no formal course work during a summer session and who will be devoting full time to thesis research.

Prerequisite: Master's student

Typically offered in Summer only

CBS 699  Master's Thesis Preparation  (1-9 credit hours)  

For students who have completed all credit hour requirements and full-time enrollment for the master's degree and are writing and defending their thesis.

Prerequisite: Master's student

Typically offered in Fall, Spring, and Summer

CBS 705/BIO 705  Fundamentals of Neuroscience  (3 credit hours)  

This is a fundamental course that will provide the student with an up-to-date coverage of molecular, cellular, physiological, and circuit-based aspects of Modern Neurosciences in the Comparative Biomedical Sciences Graduate Program. Being a graduate-level class, the instructors will assume that the students have acquired some background in basic biology and biochemistry. The most important goal of this course is to train PhD students in neuroscience function and disorders, preparing them for neuroscience research. Emphasis will be placed on the systems and skills needed to pursue experimental neuroscience activities. Important components of the learning process will be presentations from neuroscience experts, class discussions, exams and in class activities.

P: BIO 488 or permission of instructor

Typically offered in Fall only

CBS 711  Applications in Reproductive Physiology  (2 credit hours)  

Students with advanced interests in Theriogenology will meet weekly to discuss a wide range of current topics surrounding animal reproduction, including comparative physiology and endocrinology, reproductive management, reproductive pharmacologic/technologic advances in Theriogenology. Each student will be expected to present 2-3 topics with typed, referenced notes and an oral presentation. All students will be expected to actively participate in group discussions and briefly present a review of one topic-related article from the past 5 years during each lecture.

Typically offered in Fall only

CBS 712  Reproductive Management and Disease in Domestic Animals  (1 credit hours)  

Students will meet every other week to review current literature and discuss a wide range of topics surrounding animal reproduction, focused on clinical causes of infertility and their treatments in domestic and non-domestic species. Students will explore 3-5 preassigned questions surrounding a particular topic and prepare an in-depth handout answering those questions prior to arrival. Each student will be expected to actively participate in group discussions

Typically offered in Fall and Spring

CBS 713  Zoonoses and Public Health  (3 credit hours)  

Enrollment to graduate veterinarians, MVPH, MPH, or other graduate students. Veterinary students will be considered for enrollment after consultation with the course coordinator.

Prerequisite: VPH 580 or equivalent, ST 511 or equivalent

CBS 750  Techniques in Pharmacological Research  (2 credit hours)  

Theory and applications of modern scientific instrumentation to analysis of tissues, body fluids and drugs in pharmacological research. Discussion of appropriate aspects of the pharmacological use of spectroscopy, microscopy, chromatography, electrophoresis, radioisotope usage and centrifugation.

Prerequisite: BCH 452B or CH 315 or Equivalent and Graduate standing

Typically offered in Spring only

CBS 754  Epidemiology II  (3 credit hours)  

Study design, data management, and statistical analysis including applications of logistic regression and survival analysis. Main focus on descriptive, analytical and experimental epidemiology pertinent to disease etiology and prevention.

Prerequisite: Graduate standing

Typically offered in Fall and Spring

CBS 760  Molecular Technologies for Epidemiologic Investigation  (3 credit hours)  

The course is designed to help students refine their ability to select and interpret molecular diagnostic technologies for epidemiologic disease surveillance and investigation.

Prerequisite: Introductory Epidemiology

Typically offered in Spring only

CBS 762  Principles of Pharmacology  (3 credit hours)  

The action of drugs in animals and man including basic principles of drug disposition, pharmacokinetics, drug resistance, and signal transduction. Modification of physiological processes by drugs influencing nervous, renal, cardiovascular, and endocrine systems and the antimicrobic and antineoplastics agents.

Typically offered in Spring only

CBS 764/NTR 764/PHY 764  Advances in Gastrointestinal Pathophysiology  (3 credit hours)  

This course will focus on advanced gastrointestinal physiology and the pathophysiology of deseases of relevance to scientsts involved in animal-related research. In particular, the course will cover the pathophysiology of ulceration, infectious diarrhea, ischemia, motility disorders, and inflammatory diseases of the gut. An in-depth review paper will be required based on recent literature rgarding a specific gastrointestinal disease.

Prerequisite: PHY 503, PHY 504

Typically offered in Fall only

CBS 770  Cell Biology  (3 credit hours)  

Advanced cell and organelle structure and function and recent advances in molecular biology. Emphasis on current literature and application of research procedures.

Prerequisite: BCH 451 and BIO 183 and (CH 223 or CH 227)

Typically offered in Spring only

CBS 771/TOX 771  Cancer Biology  (4 credit hours)  

A comprehensive graduate course focusing on the molecular and cellular bases of cancer. Targets of oncogenic mutations will be discussed as well as their impact on cell proliferation, cell survival, and the invasion of normal tissues by tumorigeniccells. State-of-the-art technologies to detect oncogenic mutations and characterize transformed cells will be discussed as well as therapeutic strategies for the rational treatment of cancer.

Prerequisite: CBS 770

Typically offered in Fall only

CBS 773  Advanced Developmental Biology  (2 credit hours)  

In-depth coverage of current concepts and new research technologies in developmental biology. Biochemical aspects of germ cell maturation and early development, molecular and genetic regulation of morphogenesis, cellular interaction for organogenesis, hormones and growth factors mediated cellular differentiation and growth, molecular basis of neoplasia apopotises and gene therapy.

Typically offered in Fall and Spring

CBS 774  Epidemiology Of Infectious Diseases Of International Importance  (3 credit hours)  

Discussion of infectious diseases and epidemiological principles. Stress on selected enteric, zoonotic, nosocomial diseases of worldwide importance. Consideration of population dynamic techniques related to host-vector-agent.

Typically offered in Fall only

CBS 780  Veterinary Production Epidemiology  (2 credit hours)  

Examination of tools, limits, advantages and disadvantages specific to veterinary epidemiology and its execution. Assessment of means of disease prevention and outbreak investigation; mathematical simulation and economics; plus monitoring and evaluation of disease control programs; use of a multiple-species orientation. Application of the above epidemiologic techniques and their roles in assisting producers, practitioners and regulators.

Typically offered in Spring only

CBS 783/IMM 783/MB 783  Advanced Immunology  (3 credit hours)  

In depth study of the basic cellular and molecular mechanisms of immunity, including antigen processing and presentation, T cell development, initiation of the immune response, effector mechanisms, and immunological memory. The course is designed for advanced graduate students who wish to focus on the current concepts in immunology.

Prerequisite: MB (IMM) 751

Typically offered in Fall only

CBS 785  Advanced and Molecular Pharmacology  (2 credit hours)  

A course for graduate students providing a comprehensive investigation of current topics in Pharmacology with an emphasis on molecular and cellular approaches in lecture and discussion formats. Faculty will introduce each subject area and students will read recent articles, present seminars, and write professional-grade papers.

Prerequisite: CBS 762

CBS 787  Pharmacokinetics  (3 credit hours)  

Mathematical models to describe disposition of drugs and toxic chemicals in the animal body. Areas including classic compartmental and nonlinear models as well as physiological approaches. Discussion of application of these techniques to toxicologicstud

Prerequisite: CBS 560, working knowledge of calculus

Typically offered in Fall only

CBS 795  Special Topics in Comparative Biomedical Sciences  (1-6 credit hours)  

Special Topics in Comparative Biomedical Sciences

Prerequisite: Graduate Students, DVM or equivalent degree

CBS 800  CBS Seminar  (1 credit hours)  

Presentation and discussions on ongoing research and current topics in biomedical sciences.

Typically offered in Fall only

CBS 803  Seminar in Surgical Pathology  (1 credit hours)  

Description and interpretation of microscopic changes in tissues from diseased domestic and laboratory animals. Students attend and participate in a one-hour weekly seminar where microscopic lesions described, interpreted and discussed.

Prerequisite: Those holding the DVM or equivalent degree

Typically offered in Fall and Spring

CBS 804  Seminar in Necropsy Pathology  (1 credit hours)  

Description and interpretation of gross changes in tissues from diseased domestic animals. Students attend daily (M-F) 15-to 30-minute review of necropsy lesions presented by a member of the graduate staff.

Prerequisite: Those holding the DVM or equivalent degree

Typically offered in Fall and Spring

CBS 805/BIO 805  Special Topics in Neuroscience  (1 credit hours)  

Topics in neuroscience. This course will provide an opportunity for students to integrate and apply knowledge and skills gained from their graduate studies. Emphasis will be placed on primary literature, scientific practice, and on effective, professional communication and presentations. Topics and instructors will vary from semester to semester. Priority will initially be given to graduate students participating in the neuroscience concentration; other students with the necessary prerequisites will be admitted on a space available basis.

R: Grad Standing or Instructor Approval

Typically offered in Spring only

CBS 810  Special Topics  (1-6 credit hours)  

Designed to present new or special subject matter within the scope of pathology, veterinary microbiology, morphology or pharmacology. The studies may include independent investigations, seminars and/or formal lectures.

Prerequisite: Senior standing or Graduate standing

Typically offered in Fall, Spring, and Summer

CBS 812  Special Topics Pathology  (1-6 credit hours)  

Specific topics of study assigned in various laboratories involved in veterinary microbiology investigation. Students conduct in-dept studies of assigned problem areas.

Prerequisite: Those holding the DVM degree

Typically offered in Fall and Spring

CBS 813  Special Topics Laboratory Pharmology  (1-6 credit hours)  

Involvement in practical participation in the normal research activities of different laboratories working in pharmacological research. Students pursue a semi-independent project.

Prerequisite: Graduate standing

Typically offered in Fall, Spring, and Summer

CBS 816  Advanced Topics In Immunology  (1 credit hours)  

Selected topics of current interest in immunology. A different topic will be covered each semester to focus on the most recent developments in the field.

Typically offered in Fall and Spring

CBS 817  Advanced Topics In Zoological Medicine I  (2 credit hours)  

Selected topics of current interest in clinical zoological medicine focused on marine mammals, fish, reptiles, amphibians, waterfowl, ratites, raptors and medical issues in free-ranging wildlife. Review of current clinical and basic science literature, student-lead discussion sessions and participation in faculty-lead discussions.

Prerequisite: Graduate standing or enrollment in DVM curriculum

Typically offered in Fall only

CBS 818  Advanced Topics in Zoological Medicine  (2 credit hours)  

This course provides breadth and depth of knowledge in zoological medicine to prepare Zoological Medicine residents to pass American College of Zoological Medicine (ACZM) boards. Veterinary students are exposed to more in depth information related to zoological medicine than covered in their core curriculum. Each Fall (CBS 817) and Spring (CBS 818) semesters, different aspects of zoological medicine are covered. Topics rotate every 3 years so that all major groups of animals within the sub-groups, avian, aquatic, herptile, wildlife, and zoo are addressed.

Prerequisite: Graduate standing or enrollment in DVM curriculum

Typically offered in Spring only

CBS 820  Special Problems  (1-6 credit hours)  

Selection of a subject by each student on which to do research and write a technical report on the results. The individual may choose a subject pertaining to his or her particular interest in any area of study in CBS.

Typically offered in Fall and Spring

CBS 885  Doctoral Supervised Teaching  (1-3 credit hours)  

Teaching experience under the mentorship of faculty who assist the student in planning for the teaching assignment, observe and provide feedback to the student during the teaching assignment, and evaluate the student upon completion of the assignment.

Prerequisite: Doctoral student

Typically offered in Fall, Spring, and Summer

CBS 890  Doctoral Preliminary Examination  (1-9 credit hours)  

For students who are preparing for and taking written and/or oral preliminary exams.

Prerequisite: Doctoral student

Typically offered in Fall, Spring, and Summer

CBS 893  Doctoral Supervised Research  (1-9 credit hours)  

Instruction in research and research under the mentorship of a member of the Graduate Faculty.

Prerequisite: Doctoral student

Typically offered in Fall, Spring, and Summer

CBS 895  Doctoral Dissertation Research  (1-9 credit hours)  

Dissertation research.

Prerequisite: Doctoral student

Typically offered in Fall, Spring, and Summer

CBS 896  Summer Dissertation Research  (1 credit hours)  

For graduate students whose programs of work specify no formal course work during a summer session and who will be devoting full time to thesis research.

Prerequisite: Doctoral student

Typically offered in Summer only

CBS 899  Doctoral Dissertation Preparation  (1-9 credit hours)  

For students who have completed all credit hour, full-time enrollment, preliminary examination, and residency requirements for the doctoral degree, and are writing and defending their dissertations.

Prerequisite: Doctoral student

Typically offered in Fall, Spring, and Summer